Epidemiological and bacteriological profiles in children with burns.pdf

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Epidemiological and bacteriological profiles in children with burns.pdf

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Epidemiological and bacteriological profiles in children with burns

Epidemiological and bacteriological profiles in children with burns Amjed Fekih Hassen *, Sonia Ben Khalifa, Mayssa Daiki Department of Anaesthesia and Intensive Care, Children’s Hospital, Tunis El Manar University, Bab Saadoun 1007, Tunis, Tunisia b u r n s 4 0 ( 2 0 1 4 ) 1 0 4 0 – 1 0 4 5 a r t i c l e i n f o Article history: Accepted 29 October 2013 Keywords: Infection Children Burn Bacteria a b s t r a c t Objectives: The aim of our study is to determine the most prevalent bacteria responsible for nosocomial infection (NI) in burned children. Materials and methods: A prospective analytic study was conducted over a period of 30 months at the Children’s Hospital of Tunisia. All burned children were enrolled. Results: A total of 185 children were hospitalised during the study period. The mean age was 30 months (interquartile range, IR:18; 48). The gender ratio of the study population was 1.3 (104 males and 81 females). The mean total body surface area burned (TBSA) was 10% (IR:6; 16). The incidence rate of NI was 39.1 NIs per 1000 patient-days and two-thirds of the infections were polymicrobial. The most common isolated micro-organisms were methi- cillin-susceptible Staphylococcus aureus (MSSA, 57.7%), wild-type Pseudomonas aeruginosa (35.9%) and wild-type Enterobacter cloacae (26.9%). The case fatality rate was 5.9% correspond- ing to a crude death rate of 1.32 deaths per year. Septic shock with multiple organ failure was the leading cause of death. Conclusion: The most common micro-organisms responsible for NI in our series were of the wild-type phenotype. Thus, on suspicion of sepsis, empiric antibiotic treatment combining piperacillin, oxacillin and gentamicin can be proposed until identification of the causative microorganism is available. # 2013 Elsevier Ltd and ISBI. All rights reserved. Available online at ScienceDirect journal homepage: /locate/burns1. Introduction Infectious complications are one of the most important and potentially serious complicati