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CT screening lung biopsy
AJR:198, February 2012 351
ules that after investigations are proven to be
benign) [4, 10–12]. These investigations, often
invasive, result in related morbidities and mor-
talities, potentially offsetting the survival ben-
efit from the early lung cancer detection.
The International Early Lung Cancer
Action Project (I-ELCAP) developed a
straightforward algorithm for assessing in-
determinate nodules that would provide
the inclusion diagnosis of lung cancer [1].
This study protocol provides a definition for
suspicious pulmonary nodules and recom-
mends a diagnostic regimen to be followed
once these nodules are described. The proto-
col provides suggestions only; the exact de-
cision for the follow-up strategies is left to
the patient and physician and depends on the
expertise of the institution.
CT Screening for Lung Cancer:
Implication of Lung Biopsy
Recommendations
Ute Wagnetz1
Ravi J. Menezes2
Scott Boerner3
Narinder S. Paul2
Dirk Wagnetz4
Shaf Keshavjee5
Heidi C. Roberts2
Wagnetz U, Menezes RJ, Boerner S, et al.
1Department of Radiology, GZO Spital Wetzikon,
Wetzikon, Switzerland.
2Joint Department of Medical Imaging, University Health
Network, Mount Sinai Hospital and Women’s College
Hospital, 76 Grenville St, Room W272, Toronto, ON M5S
1B2, Canada. Address correspondence to H. C. Roberts
(heidi.roberts@uhn.on.ca).
3Department of Pathology, University Health Network,
Toronto, ON, Canada.
4Department of Thoracic Surgery, University Hospital
Freiburg, Freiburg, Germany.
5Department of Thoracic Surgery, University Health
Network, Toronto, ON, Canada.
Cardiopulmonar y Imaging ? Or ig ina l Research
AJR 2012; 198:351–358
0361–803X/12/1982–351
? American Roentgen Ray Society
T
he advent of low-dose helical CT
screening introduced for the early
detection of lung cancer in the ear-
ly 1990s has generated a wide-
spread interest, resulting in the diagnosis of a
high number of pulmonary nodules and early-
stage peripheral lung cancers [1–6]. In di
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