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Effect of the osmolarity change in multipurpose solutions induced by an improper contact lens case cleaning procedure.pdf
Contact Lens and Anterior Eye 39 (2016) 177–184
Contents lists available at ScienceDirect
Contact Lens and Anterior Eye
journal homepage: /locate/clae
Effect of the osmolarity change in multipurpose solutions induced by an improper contact lens case cleaning procedure
José Pinto-Fragaa,b, Antonio Abengózar-Velaa,b, Alberto López-Miguela, Vicente Martín-Monta?éza,b, Alberto López de la Rosaa,b, María J. González-Garcíaa,b,*
a Instituto de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid, Valladolid, Spain b CIBER-BNN, Valladolid, Spain
ARTICLE INFO
Article history: Received 28 January 2015 Received in revised form 4 January 2016 Accepted 29 January 2016
Keywords: Contact lens Contact lens case cleaning Osmolarity
ABSTRACT
Purpose: To determine whether variations in multipurpose disinfecting solution (MPDS) storage osmolarity from inappropriate contact lens (CL) case cleaning affect ocular surface integrity and wearer comfort. Methods: There were twenty contact lens cases (study CLCs) in the study group. Ten were ?lled with ReNu Multiplus1 and 10 with SoloCare AquaTM (MPDS-1 and -2, respectively) and kept closed for 8 h; the cases were then emptied and kept open for air-drying for 16 h. This procedure was carried out every day for two months. Storage solution osmolarity was measured on days 0, 15, 30, 45 and 60. Ten subjects were then ?tted with both month-old lenses stored in the study CLCs and with new lenses stored in new cases with fresh solution for 24 h (control CLCs). Symptoms, tear osmolarity and percentage of subjects whose conjunctival hyperaemia and ocular surface staining scores changed were determined after 1 h of wear. Results: Study CLC osmolarity increased in both solutions after two months (p 0.05). For MPDS-1 there were differences in stinging between study CLCs and control CLCs after 10 min of CL wear (p = 0.04), and in comfort after 10 (p = 0.035) and 60 min wear (p = 0.042). Signi?cant (p 0.05) differences between study CLC and control
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