肾性贫血铁剂的使用.PDFVIP

[1] [2] 70% 2 (red bleed cell indices) (reticulocyte count) (serum iron) (percent transferring saturation, TSAT) (ferritin) 20% 10 ng/ml deficiency) 100 ng/ml [3] (functional iron 100 ng/ml block) ( 20%) (inflammatory 100 ng/ml inflammatory block 20% [4] 2006 (NKF-DOQI guideline) : EPO [5] 2006 (NKF- DOQI guideline) 2001 1. Serum ferritin 100 ng/ml and transferring saturation (TSAT) 20% 2. : Serum ferritin 200 ng/ml and transferring saturation (TSAT) 20% or content of hemoglobin in reticulocytes (CHr) 29% NKF-DOQI guideline 800 mg/mL 2006 NKF-DOQI guideline 500 ng/mL [6] 500 ng/ 142 96 19 3 mL EPO dextran Iron gluconate Iron sucrose dextran Iron Iron gluconate Iron sucrose 2006 NKF-DOQI guideline [7-8] 325 65 NKF-DOQI guideline 200 ferrous sulfate ) ( sodium ferric gluconate dextran Iron dextran Iron sucrose Iron , 40% [9] Iron dextran dextran dextran Iron (25 5) 50 [10] 31.25 125 sodium ferric gluconate 25 100 Iron sucrose 50 100 30 100 Iron dextran 125 sodium ferric gluconate 100 Iron sucrose ( 1000 ) ( 20% 100 200 ng/mL ) 31.25 125 sodium ferric gluconate 25 100 Iron sucrose 20 25% 50% 200 ng/mL 100 ng/mL ( 500 ng/mL) Iron dextran 300 400 sodium ferric gluconate 1000 500 1000 Iron sucrose 250 [6] 96 19 3 143 1. Eschbach JW, Cook JD, Scribner BH, Finch CA: Iron balance in hemodialysis patients. Ann Intern Med 1977; 87: 710. 2. USRDS 2005 Annual Report: ESRD clinical performance measures project. Am J Kidney Dis 2006; 48: S1. 3. Fernandez-Rodriguez AM, Guindeo-Casasus MC, MoleroLabarta T, et al: Diagnosis of iron deficiency in chronic renal failure. Am J Kidney Dis 1999; 34: 508. 4. Patruta SI, Edlinger R, Sunder-Plassmann G, Horl WH: Neutrophil impairment associated with iron therapy in hemodialysis patients with functional iron deficiency. J Am Soc Nephrol 1998; 9: 655. 5. K/DOQI Clinical Practice Guidelines and Clinical Practice Recommendations for anemia in Chronic Kidney Disease. Am J Kidney Dis 2006; 47: S1. 6. 2007 UpToDate. Iron balance in dialysis pa