中药成分代谢化学教学大纲.doc

课程教学大纲： teaching outline 课程性质和任务 Nature and task of the course 中药成分代谢化学是研究中药有效成分在动物及人体内代谢反应的一门学 Chinese native medicine ingredient metabolic chemistry is the subject of researching Metabolic reactions of traditional Chinese medicine’s effective component in animals and humans’ body. 科。主要任务是：1.中药成分在机体内发生代谢反应的组织、器官、部位及 The main task: 代谢反应发生的条件。2.代谢产物的定量分析及原形成分和代谢产物在体 The Tissue,?organs,?parts of Chinese herbal medicinal’s ingredients metabolic reactions in the body and the condition of the reactions 内或某组织器官的动态变化。3.代谢反应的机理及代谢途径。4.代谢产物的 Quantitative analysis of the metabolites and the dynamic changes of original components and metabolites in the body or some organs. 3 The mechanism?and metabolic pathway of?metabolic reactions 药效评价，新药的设计创新。5.代谢产物的提取分离、精制及结构测定。6. 4pharmacodynamic evaluation of metabolic products and design innovation of new drugs. 5 metabolic products’ extraction、separation、purification and structure determination 新的代谢化学研究方法的探讨。 6To explore the?new researching methods?of?Metabolic chemistry 课程教学目标： Course Teaching target 中药代谢化学是研究、整理提高祖国医药遗产的现代科学之一。 Chinese native medicine ingredient metabolic chemistry is the one study of modern science that can research and arrange the legacy of traditional chinese medicine 对阐明中药的有效性，探讨有效成分的作用原理，解释中药复方配伍的合理性，阐明中医辩证施治的科学内涵等都具有重要意义。 It is very significant to elucidate the effectiveness of traditional Chinese medicine、to explore the function mechanism of effective components、to explain the rationality of compatibility of compound chinese medicine and to clarify the scientific connotation of traditional Chinese medicine. 此外，也是中药成分药代动力学和生物利用度研究的基础和前提。 In addition, it is the foundation and the premise of traditional chinese medicine composition of pharmacokinetics and bioavailability researching 中药成分代谢化学的研究还为新的活性成分的发现、新药合成及新的前体药物的研制提供可贵的理论和实践的依据。 The research of Chinese native medicine ingredient metabolic chemistry also provide valuable theory and practical basis for new active ingredients discoverying、new drugs composin