玻璃酸钠臭氧间断注射液治疗膝关节骨关节炎对比研究.docVIP

玻璃酸钠、臭氧间断注射治疗膝关节骨性关节炎的对比研究 韩俊松 余生源 浦创 王文 （中国十九冶集团有限公司职工医院康复医学科，攀枝花 617000） 【摘 要】 目的 比较臭氧、玻璃酸钠关节内不同时间注射治疗膝关节骨性关节炎的临床疗效。方法 将184例膝关节骨性关节炎患者随机分为治疗组和对照组，治疗组91例，对照组93例。治疗组采用臭氧关节内注射后第2天注射玻璃酸钠；对照组采用臭氧、玻璃酸钠同时关节内注射，比较两组不同时间节点的VAS评分及疗程结束后3月的疗效。结果 两组患者VAS评分较治疗前均有下降(P0.05)，治疗组VAS评分在治疗的1、2、3周较对照组下降更明显(P0.05)，差异有统计学意义。治疗组总有效率为92.30%高于对照组的83.87%,差异有统计学意义(P0.05)。结论 玻璃酸钠、臭氧关节内间断注射是治疗膝关节骨性关节炎有效手段，优于传统同时注射。 [Abstract] Objective Comparison of the clinical efficacy of ozone, sodium hyaluronate intra-articular injection of different time treatment of osteoarthritis of the knee. Methods 184 patients with knee osteoarthritis were randomly divided into treatment group and control group, treatment group 91 patients and control group 93 patients. Treatment group were treated with ozone intra-articular injection of sodium hyaluronate injection after second days; The control group using ozone, intra-articular injection of sodium hyaluronate and, In March the VAS score and the treatment effect of different time points were compared between the two groups after the end of the. Result Two groups of patients with VAS score than before treatment were decreased (P0.05), VAS score of the treatment group in the treatment of 1, 2, 3 weeks than the control group decreased significantly (P0.05), the difference was statistically significant. The total effective rate of treatment group was 92.30% higher than 83.87% in the control group, the difference was statistically significant (P0.05). Conclusion Sodium hyaluronate, ozone joint intermittent injection is an effective means of treating osteoarthritis of the knee, is superior to the traditional simultaneous injection. 【关键词】 臭氧 玻璃酸钠 骨性关节炎 膝关节 [Keyword] Ozone Sodium hyaluronate Osteoarthritis Knee joint 玻璃酸钠联合臭氧同时关节腔注射治疗膝骨性关节炎[1]是近年来国内外盛行的一种疗法，疗效较为满意，且能缩短单独玻璃酸钠治疗的疗程。因玻璃酸钠、臭氧均需相对独立的作用环境，同时应用二者可能相互影响，故我们采取臭氧注射后第2天再注射玻璃酸钠治疗膝骨性关节炎（OA），效果满意，现报道如下： 1 材料与方法 1.1 一般资料 2011年5月至2012年12月我院康复医学科门诊及住院膝关节骨关节炎患者184例，随机分成两组：1、治疗组91例，男性41例，女性50例，年龄（60.2±9