NewerAEDs资料.ppt

Current diagnosis treatment of epilepsy ;1. WHO世界五个主要防治的神经精神疾患;2. Common Questions of Epilepsies;3.癫癎患病率;年龄;癫癎发病:男女;4. 癫癎类型;v;Definition of ILAL,IBE,2004;国际抗癫痫联盟-ILAE,2005年癫痫的定义; 6.癫癎:是一组慢性复发性疾病;7. 癫癎的电生理本质;8. 癫癎的病因;9. 癫癎发作分类,癫癎病因分类;In general,总的来说,;10. Epileptic seizure; 癫癎发作特点;11. 癫癎持续状态（status epilepticus, SE），;癫癎持续状态3个时相(phases),持续状态发作前期、发作期及发作后意识模糊期。;12. Epileptic syndromes; 婴幼儿癫癎综合征: Epileptic encephalopathies;13. 婴儿痉挛(强直痉挛发作,tonic spasms); 14. 癫癎Ep, 热性惊厥FS; 热性抽搐（febrile seizures ,FS）; 复杂性热性抽搐,complex FS; 复发性(recurrent)热性抽搐;15. 热性抽搐附加症(FS plus, FS+);16. Status epilepticus; Authority References;17. Electroencephalography (EEG); EEG;18. EP-定性（病因）诊断“vindicates”;19. treatment steps: acronyms- CONVULSIONS; 20. 2004 -UK国家临床最佳研究(NICE) ;癫癎不是一个独立的疾病;21. Clinical manifestations (semiology);22. 全面性(generalized)发作的类型;23.癫癎诊断新趋势;24. 癫癎五层次诊断;25. 由卫生部主管、民政部登记注册的国家一级协会——中国抗癫癎协会在北京成立;由卫生部组织实施的“中国农村地区癫癎防治管理项目”;26. epilepsies-ILAE;27.NICE (The National Institute for Clinical Excellence NICE Issue Date March2004;28. NICE治疗新趋势（2）;29. NICE治疗新趋势（3）;30. NICE治疗新趋势（4）个性化治疗;31. EUCARE -European White Paper on Epilepsy -Europe三大新趋势;32. General goals of epileptic medications; 33. Treatment of EP.;34. Basic principles of drug treatment; 35. 癫癎的治疗原则;36. 发作类型与选药(selection of AEDs);37. 强调癫癎最重要的是控制发作;38. 疗效efficacy;;AEDs for Ep. syndromes( NICE, 2004）;39.Antiepileptic drugs selection:considerations in the real world; 40. Advantages of monotherapy ;41. Are newer AEDs better than old AEDs ?;42. New AEDs are not proven to have efficacy than the AEDs; 43. Newer AEDs be used;what order of priority the new AEDs should used? In ;Rational polytherapy of focal epilepsies;Monotherapy insufficient effecacy indeed, changes to other one drug, then bi-drugs(bi-therapy), at most tri- drugs(tri-therapy).Combined with different anti-epileptogenesis、HEIs, HEInds, pharmacokinetics(PK), pharmacodynam