Obesity Is a Major Determinant of Radiation Dose in Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation》.pdfVIP

Journal of the American College of Cardiology Vol. 50, No. 3, 2007 © 2007 by the American College of Cardiology Foundation ISSN 0735-1097/07/$32.00 Published by Elsevier Inc. doi:10.1016/j.jacc.2007.03.040 Obesity Is a Major Determinant of Radiation Dose in Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation Joris Ector, MD,* Octavian Dragusin, MS C,† Bert Adriaenssens, MD,* Wim Huybrechts, MD,* Rik Willems, MD, PHD,* Hugo Ector, MD, PHD,* Hein Heidbüchel, MD, PHD* Leuven, Belgium Objectives This study sought to evaluate the impact of obesity on patient radiation dose during atrial fibrillation (AF) abla- tion procedures under fluoroscopic guidance. Background Obesity is a risk factor for AF and its recurrence after ablation. It increases patient radiation dose during fluoro- scopic imaging, but this effect has not been quantified for AF ablation procedures. Methods Effective radiation dose and lifetime attributable cancer risk were calculated from dose-area product (DAP) measure- ments in 85 patients undergoing AF ablation guided by biplane low-frequency pulsed fluoroscopy (3 frames/s). Three dose calculation methods were used (Monte Carlo simulation, dose conversion coefficients, and depth-profile dose curves). 2 2 Results Median DAP for all pati