《医学传媒cardiology--英文教学1(AS)》.pptVIP

Coronary Heart Disease Bian Bo, Dong Shaozhuang Cardiovascular Center Tianjin Medical University General Hospital No.1 Killer World China USA In different countries, 25-45% death are caused by cardiovascular disease. Mortality of cardiovascular disease(per 100,000）：male, highest in Russia，1310，lowest in Japan, 201；female, highest in Russia, 581，lowest in France, 84. China In China, 1 year, 10 million new CHD patients. In China, per 15 seconds 1 people will die because of CVD. In China, 1 year 2.6 million people will die because of CVD. USA 1995，USA, 960,000 die because of CVD, 42% of total mortality，No.1 cause in male45y, and in female65y Total CVD patients in USA ,58 million，20% of total population Causes of CVD major cause atherosclerosis (AS) Other Causes Inflammation---Kawasaki syndrome Emboli-----------young male, dehydration Spasm-----------Prinzmetals angina Injury-------------trauma Ⅰ Atherosclerosis A kind of clinical vascular disease Atherosclerosis Atherosclerosis is an ongoing process affecting mainly large- and medium-sized arteries; it can begin in childhood and progress throughout a person’s lifetime. Atherosclerosis Unstable atherosclerotic plaques may rupture, leading to the formation of a platelet-rich thrombus that partially or completely occludes the artery and causes acute ischemic symptoms. What Are the Results of Atherosclerosis? Results: silence ischemia---angina pectoris, TIA, claudication ... necrosis---MI, stroke... fibrosis---ischemia cardiomyopathy/nephropathy/dementia... Ⅱ Risks Factors Ⅱ Risks of Atherosclerosis Age Family history Gender Cigarette smoking Low-density lipoprotein cholesterol (dyslipidemia) Hypertension Diabetes mellitus Estrogen deficiency Inactivity Obesity others: A-type character, high TG, high homocysterine... Unmodifiable risks Modifiable risks 2.1 Unmodifiable risks Age Family history Gender Age - unmodifiable risks(1) Chances of a person having atherosclerosis are directly proportional to age. peak