中医药心力衰竭动物模型的研究现状邓青秀.pdf

2011 30 2 Sichuan Journal of Zoology ol30 No2 2011 DOI: 10. 3969 / j. issn. 1000- 7083. 2011. 02. 024 邓青秀, 彭成* ( 成都中医药大学, 成都 610075) : ; , , , : ; ; ; : Q9533; R54 16 : A : 1000- 7083( 2011) 02- 0296- 05 Research Status on theHeartFailureAnimalModel * DENG Q ingx iu, PENG Cheng ( Chengdu University of T raditional Ch ineseM edi ine, Chengdu 6 10075, Ch ina) Abstract:H eart failure is a ommon lin i al ardiovas u lar syndrom e. H eart failure anmi almodels m ainly in lude anmi al disease m odel and om b ining syndrom ew ith d isease. Common ly rep li ated m ethods of the an mi al d isease m odels in lude: abdom inal aorta onstri tion, oronary artery ligation, rap id ventri u lar pa ing, intravenous inje tion of pentobarbital sod i um, Adriam y in m ethod and Isoproterenol inje tion. Comb in ing syndrom ew ith d isease anmi alm odels in lude: a ute heart failure w ith heartY ang defi ien y syndrom e, heart failurew ith heart Q i defi ien y syndrom e, heart failure w ith k idneyY ang defi ien y syndrom e, hron i heart failurew ith Q i defi ien y and blood stasis syndrom e, heart failure w ith heart and k idney Y ang defi ien y syndrom e, hron i heart failure w ith Y ang defi ien y w ith w ater retention, and heart failurew ith Y in defi ien y w ith internal heat. W e should sele t the proper heart failure an mi alm odel, in lud ing sele ting the proper an mi al and know the prin ip le of an mi al model establishm ent to ensure that the expermi ental resu lts are s ientifi and reliab le. Keywords: heart failure; an mi alm odel; an mi al disease m ode;l om bin ing syndrom e w ith disease ( heart failure, ) ,