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临床肿瘤学(2003年英文版)第24章-第33章chapter25【荐】.pdf
25
ANCER IS DIAGNOSED ANNUALLY IN APPROXI-
C
Pediatric Solid mately 8,400 US childre nyounger tha nage 15.
Cancer is the second major cause of mortality i nthis
populatio n(see Chapter 1). Childhood cancers differ
Tumors from adult cancers as regards their origins and histologic
subtypes, their etiologic characteristics, their response
to treatment, and the outcomes. I nthe adult popula-
tion, epithelial cancers are most common, and many are
related to environmental carcinogens. More commonly,
pediatric malignancies are of hematopoietic origi nor
are primary central nervous system (CNS) tumors. This
chapter reviews the epidemiologic factors, pathologic
Karen C. Marcus
features, clinical presentation, and treatment of pediat-
ric solid tumors. Despite the small number of cases of
childhood cancers (i ncontrast with the numbers i nthe
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