深圳普通劳务工妇女人群生殖道支原体感染情况及耐药分析.docVIP

深圳普通劳务工妇女人群生殖道支原体感染情况及耐药分析 谭欣1，刘爱胜1，文艳2 ，施俊柱3 （1深圳市龙华新区人民医院检验科，广东省，518109；2 深圳市光明新区人民医院ICU，广东省，518106；3 深圳市龙华新区观澜人民医院检验科，广东省，518109） [摘 要] 目的：了解深圳普通劳务工妇女人群生殖道支原体感染及耐药情况，为早期发现、及时治疗和合理用药提供科学的参考依据。方法：采用改良肉汤稀释液体培养法对2677例深圳普通劳务工妇女人群生殖道分泌物进行支原体的培养和药敏分析，鉴定解脲脲原体(Uu)和人型支原体(Mh)，并采用断点法对13种抗菌药物的进行体外敏感性试验。结果：2677例普通劳务工妇女人群生殖道支原体感染率为35.3%(944/2677) ，其中Uu27.5%(736/2677) ，Mh1.1%(29/2677)，Uu+Mh混合感染为6.7%(179/2677) 。单独Uu感染对喹诺酮类药物有较高耐药性，最为敏感的药物为美满霉素（97.1%），其次为强力霉素（94.2%）、罗红霉素（90.7%）、交沙霉素（89.5%）及阿奇霉素（88.1%），Mh感染对大环内脂类药物有较高耐药性，而Uu+Mh混合感染中这两类药物均有耐药率均较高。结论：女性生殖道支原体感染以Uu感染为主，支原体对各种抗菌药物均产生了一定的耐药性，美满霉索、强力霉素、罗红霉素、交沙霉素和阿奇霉素等可作为治疗支原体感染的首选药物。 [关键词] 普通劳务工妇女人群；生殖道；支原体；感染率；耐药分析 Ordinary LaoWuGong women genital tract mycoplasma infection and drug resistance analysis Tan Xin 1, LiuAi-Sheng 1, Wen Yan2 ,ShiJun-Zhu 3 (1 shenzhen longhua new district peoples hospital clinical laboratory, guangdong province,518109; 2 shenzhen guangming new district peoples hospital ICU, guangdong province, 518106; 3 shenzhen longhua new district guan lan peoples hospital clinical laboratory, guangdong province, 518109) [abstract] objective: to understand the shenzhen LaoWuGong ordinary women genital tract mycoplasma infection and drug resistance situation, for the early detection and timely treatment and rational drug use to provide scientific reference basis. Methods: using improved broth dilution liquid culture method in 2677 cases of shenzhen ordinary LaoWuGong women genital tract secretions of mycoplasma culture and drug susceptibility analysis, identification of ureaplasma urea urealyticum (Uu) and mycoplasma type (Mh), and by the method of breakpoint, 13 kinds of antimicrobial susceptibility test in vitro. Results: 2677 cases of normal LaoWuGong women genital tract mycoplasma infection rate was 35.3% (944/2677), including Uu27.5 % (736/2677), Mh1.1 % (29/2677), Uu + Mh mixed infection was 6.7% (179/2677). Separate Uu infection has higher resistance to quinolones, the most sensitive drugs for happy amphotericin