高度宫颈上皮内瘤变检测高危型HPV的意义.pdfVIP

·5133· 高度宫颈上皮内瘤变检测高危型HPV的意义① 宋丽君 陈 碧 庞江琳 罗桂香广东医学院附属医院(广东’湛江) 524001 中国图书分类号m73．11737．33文献标识码A 文章编号1∞14411(2007l靳-$133-03 【摘要】 目的：评价检测高危型人乳头瘤病毒(HumanPapiilomavirtmre,v)对筛查高度宫颈上皮内瘤变的价值。方法： 变的价值。结果：780例妇女中，HPV感染发生率为21．3％，CINH及以上的检出率(72．5％)高于CINI(23．5％)，两者差 变可选用的方法，联合液基细胞学检测有较高的灵敏度和阴性预测值。 【关键词】 宫颈上皮内瘤变人乳头瘤病毒DNA液基细胞学 risk for neo- The ofthe HPVDNAtest significancehigh highgradeintraepithelial plasiascreening SONG a1．Institute and Li—Jun，CHENBi，PANGJiang一胁，et of Obstetrics，Aj筛liatedHosp办alofGuang- Gynecology Medical 524001，Guangdong，China 面，lg College，Zhanjiang thevalueofHPVDNA Objective：Toinvestigate II)for imraepithelial {Abstract) test(hybridcapture hish印Ide the of case8were thetwomemedswere咖· HCⅡtestand based 780 neoplasia．Methods：Theliquid c”dogy performed．The她sul协of WaS tOevaluatethe ofHCIItestfor cervical the whichtaken船 pared efficacy hi【曲grade neoplagiascreeningby colpescopiebiopsies incidenceofhuman infectionWaS21．3％．ThedetectionrateofHPVin ne,- standard．Results：The papillomaviral hi曲gradeimraepithelial ratewasfounda． thanthatinlow infection oplagia(72．5％)Wallsignificandyhigher gradeintraepithelialneoplasia(23．5％)．Thehigher women26-55thantheother