促红细胞生成素的临床应用进展.pdfVIP

# 992# 中华全科医学 2009年 9 月第 7卷 第 9期 Ch inese Journal ofGen eral Practice, Septemb er 2009, Vol17, N o19 = 促红细胞生成素的临床应用进展 , , , , , = ( Erythropoietin, EPO), 。 EPO , EPO, 、、、、, 。EPO, , EPO 。 = ( EPO );; ; = R347 R363. 22 = A = 167424152( 2009) 0920992203 A dv an ces of C lin ica l App lica t ion of Er ythr op o ie t in YANG Yuan2sheng, CHEN Ken, SHIXing2liang, et al. InternalMedicine Teaching and Research Section, ClinicalMedicineCollege, Guangdong Phar aceuticalUniversity,Guangdong 510310, China = Ab str ac t To comprehen the applie status quo, explore an evelop new usingways of erythropoietin( EPO ) in clin ical practice, we retrieve the recent papers on the clin ical application ofEPO both at hom e an abroa . A s the stu y upon EPO con2 tinue , m any biological functions ofEPO wh ich has evoke peop le. s great interest in stu y ha been iscovere , such as promo2 ting erythropoiesis, ant2i in flamm atory response, anti2apoptosis, protective cell an enhancem ent mi mune function an so on. In al2 most all the system s an organs, EPO, as amulti2functional cell factor, has targets. It provi es theoretical evi ences forEPO that it ha a potential an wi e app licational perspective in clin ic. =K ey w ord s E rythropoietin(EPO) ; Inflamm ation inh ib ition; Cytoprotection; Clinical app lication EPO是一种能有效刺激红细胞生成的内分泌激素, 它主要 [ 1] Ferruh A等 以无慢性肾脏疾病患者正常 EPO 反应为依据提 作用于骨髓造血细胞, 促 红系祖细胞增生、分化最终生成成 出了通过测量 EPO表达百分比浓度的新的定量方法校正严重