胃蛋白酶原Ⅰ联合胃泌素-17检测对慢性萎缩性胃炎发病部位及胃癌进展时期的预测价值.pdfVIP

窑医学检验 窑 中国当代医药 2014年9月第21卷第25期 胃蛋白酶原Ⅰ联合胃泌素-17检测对慢性萎缩性 胃炎发病部位及胃癌进展时期的预测价值 周海平 江西省宜春市人民医院老干科袁江西宜春 336000 [摘要] 目的探讨胃蛋白酶原 玉渊PG玉冤联合胃泌素-17渊G-17冤检测对慢性萎缩性胃炎发病部位及胃癌进展时期 的预测价值遥 方法选择本院收治的慢性萎缩性胃炎患者33例尧胃癌患者35例作为研究对象袁进行PG 玉尧PG域 和G-17检测袁比较并分析PG玉尧PG域及G-17水平的变化情况遥 结果慢性萎缩性胃炎组PG玉和G-17水平高 于胃癌组袁差异有统计学意义渊P约0.05冤袁胃窦部组的PG 玉水平高于胃体部组和全胃弥漫组袁差异有统计学意义 渊P约0.05冤袁胃体部组的G-17水平高于全胃弥漫组和胃窦部组袁差异有统计学意义渊P约0.05冤袁早期胃癌或原位癌的 PG 玉和G-17水平显著高于进展期胃癌袁差异有统计学意义渊P约0.05冤遥 结论 胃窦部发病为主的慢性萎缩性 胃炎其G-17显著下降袁胃体部或全胃病变者PG 玉的下降更加明显袁进展期胃癌者PG玉水平更低而G-17水平 更高遥 [关键词] 胃蛋白酶原玉曰胃泌素-17曰预测曰慢性萎缩性胃炎部位曰胃癌进展 [中图分类号] R446.11+9 [文献标识码]A [文章编号] 1674-4721渊2014冤09渊a冤-0126-03 The prediction vaule of pepsinogen 玉combined with gastrin-17 in lesion location of chronic atrophic gastritis andthe period of gastric cancer pro鄄 gression ZHOUHai-ping DepartmentofElderly Cadre,People忆sHospitalofYichun CityinJiangxi Province,Yichun 336000,China [Abstract]Objective To investigate the prediction vaule of pepsinogen 玉combined with gastrin-17 in lesion location of chronic atrophic gastritis and the period of gastric cancer progression. Methods 33 cases with chronic atrophic gas鄄 tritis and 35 cases in the different period of gastric cancer in our hospital were selected as research objects.All these participants were detected by pegsinogen 玉,pegsinogen域and gastrin-17.The level of pegsinogen 玉,pegsinogen域and gastrin -17were compared and analyzed. ResultsThe level ofpepsinogens I and gastrin-17 in chronic atrophic gastri鄄 tisgroupwere higher than that in gastric cancer group,with statistical difference(P约0.05).Pepsinogen I level in the gas鄄 tric antrum of chronic atrophic gastritiswas higherthan that in the gastric body and the total diffuse,with statistical dif鄄 ference (P约0.05),the gastrin-