两色金鸡菊化学成分和药理作用研究进展.pdfVIP

中国药物应用与监测 2014 年8 月第11卷第4 期 Chinese Journal of Drug Application and Monitoring, Vol.11, No.4, August 2014 ·药学进展 · 两色金鸡菊化学成分和药理作用研究进展 1 2 2 2 2 3（1.新疆医科大学中医学院，新疆 乌鲁木齐 830054 ；2.新疆医科大学 毛新民 ，卢　伟 ，李琳琳 ，王　烨 ，龙　梅 ，兰　怡 基础医学院，新疆 乌鲁木齐 830054 ；3.新疆医科大学附属中医院，新疆 乌鲁木齐 830054 ） [摘要]　两色金鸡菊原产于美国，主要作为景观植物栽培，后分布于世界各地。在我国新疆地区野生资源丰富，两色金鸡菊 含有黄酮类、挥发油类、多酚类、苯丙素类、皂苷类、氨基酸类、糖类以及脂肪酸类等化学成分，具有抗炎、抗氧化、降血压、 α 调血脂、改善凝血功能、抑制 - 葡萄糖苷酶、恢复糖耐量受损情况、降低血糖和抗菌等生物活性，具有很好的开发应用前景。 本文对两色金鸡菊化学成分和药理作用的研究文献进行综述，为其开发利用提供参考。 [关键词]　两色金鸡菊；化学成分；药理作用 [ 中图分类号]　R96　　 [ 文献标识码]　A　 [ 文章编号]　1672 – 8157(2014)04 – 0235 – 05 The progress of chemical constituents and pharmacological action of Coreopsis tinctoria Nutt. 1 2 2 2 2 3 (1. Traditional Chinese Medicinal College of Xinjiang MAO Xin-min , LU Wei , LI Lin-lin , WANG Ye , LONG Mei , LAN Yi Medical University, Urumuqi 830054, China; 2. College of Basic Medicine of Xinjiang Medical University, Urumuqi 830054, China; 3. Affiliated Traditional Chinese Medicinal Hospital of Xinjiang Medical University, Urumuqi 830054, China) [ABSTRACT]　Coreopsis tinctoria Nutt. originated in the United States, which is desirable as ornamental plant, then distributed all over the world. In China, it grows in the southern of Xinjiang as wild resources. Coreopsis tinctoria Nutt. contains flavonoids, volatile oil, phenolic, phenylpropanoids, saponins, amino acids, sugars and fatty acids, etc. The pharmacological and biological studies revealed that the plants had many activities such as anti-inflammatory, antioxidant, lowering blood pressure, regulating blood lipid, improving the function of blood coagulation, inhibiting α glycosidase enzymes, recovering the impaired glucose tolerance, - lowering blood sugar and antimicrobial biological activity, so it has