国际糖生物学战略布局与研究前沿分析.pdfVIP

· 608 · 生命的化学, 2013, 33(5): 608-616 《生命的化学》2013 年33 卷5 期 情报分析 情报分析 国际糖生物学战略布局与研究前沿分析 * 阮梅花 ，黄菲，刘晓，王慧媛 ( 中国科学院上海生命科学信息中心，上海200031) 摘要：糖生物学与细胞信号转导、发育、免疫等许多领域相关联，是全面、深入理解生命活动所必 需的。本文通过分析各国在糖生物学领域的战略布局，并使用ISI Essential Science Indicators数据库和 VOS Viewer软件从定量角度分析国际糖生物学领域的研究前沿，为我国制定糖生物学研究相关战略提 供借鉴。 关键词：多糖；糖生物学；战略布局；研究前沿 International strategic arrangement and research fronts of glycobiology RUAN Meihua*, HUANG Fei, LIU Xiao, WANG Huiyuan (Shanghai Information Center for Life Sciences, Chinese Academy of Sciences, Shanghai 200031, China) Abstract: Glycobiology correlates with cell signaling, development, immunity, etc.. Glycobiology is essential for understanding the fundamental life activities. Much attention has been paid to Glycobiology by the United States, Europe and Japan, which have provided much funds and established databases and consortium for glycobiology research. Developing countries, such as India and China, have also funded research in this field. This paper utilizes two tools (ISI Essential Science Indicators and VOS Viewer) to analyze the research fronts of glycobiology. Combining qualitative and quantitative analysis, this paper provides suggestions for the distribution and strategic deployment of glycobiology research in China. Key words: glycan; glycobiology; strategic plan; research fronts 组成生物体的四大类分子之一的多糖在受 《生化年评(Annual Review of Biochemistry)》中发 精、发育、分化、神经系统和免疫系统衡态的维 表了题为Glycobiology的综述，标志着糖生物学的 持等方面起着重要作用；炎症和自身免疫疾病、 诞生[1] 。糖生物学广义的定义是研究自然界中广泛 ( ) 老化、癌细胞的异常增殖和转移、病原体感染等