弓形虫感染蝙蝠的血清流行病学调查.docVIP

 First Report of Toxoplasma gondii Infection in Five Species 5 10 15 20 25 30 35 of Bats in China# * Abstract: Toxoplasma gondii is an obligate intracellular protozoan parasite which can infect almost all warm-blooded animals and humans with a worldwide distribution. Bats are are reservoirs for an increasing number of emerging zoonotic viruses, such as henipaviruses and severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV). However, little is known of T. gondii infection in bats. The objective of the present study was to determine the seroprevalence of T. gondii infection in bats in China. A total of 217 serum samples collected from five species of bats were collected between April 2010 and August 2011 from four provinces in China, and antibodies to T. gondii were determined using the modified agglutination test (MAT, 1:25 or higher). Antibodies to T. gndii were found in 26.5% (18/68) Megaderma lyra, 13.6% (12/88) Rousettus leschenaulti, 13.6% (3/22) Cynopterus sphinx, 20% (4/20) Vespertilio superaus and 15.8%% (3/19) Pipistrellus javanicus. Antibody titers ranged from 1:25 to 1:400 with titers of 1:200 in 4 of the 5 bat species. The present study demonstrated the occurrence of T. gondii infection in bats in China, and these bats are new hosts for T. gondii, which may pose a threat to human health. Keywords: Toxoplasma gondii; Bat; Seroprevalence 0 Introduction The protozoan Toxoplasma gondii infects almost all warm-blooded animals, including humans [1,2]. Bats are of biological interests because they are reservoirs for an increasing number of emerging zoonotic viruses, including henipaviruses, severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV), rabies viruses, and Ebola virus [3]. Little is known of T. gondii infection in bats. There are two old reports of T. gondii infection in insectivorous bats of the genus Myolis from France. Akinchina and Doby (1968) saw T. gondii in the brain of 1 Sabin Feldman dye test negative Myolis bechsteini