国会预算办公室-美国国立卫生研究院资金的变化和美国食品药品监督管理局审查时间的变化将如何影响新药的开发（英）-2025.7.pdfVIP

CONGRESSIONALBUDGETOFFICEPhillipL.Swagel,Director

U.S.Congress

Washington,DC20515

July18,2025

HonorableJeffreyA.MerkleyHonorableBernardSanders

RankingMemberRankingMember

CommitteeontheBudgetCommitteeonHealth,Education,

UnitedStatesSenateLaborandPensions

Washington,DC20510UnitedStatesSenate

Washington,DC20510

HonorableFrankPallone,Jr.HonorableBrendanF.Boyle

RankingMemberRankingMember

CommitteeonEnergyandCommerceCommitteeontheBudget

U.S.HouseofRepresentativesU.S.HouseofRepresentatives

Washington,DC20515Washington,DC20515

Re:HowChangestoFundingfortheNIHandChangesintheFDA’sReview

TimesWouldAffecttheDevelopmentofNewDrugs

DearRankingMemberMerkley,RankingMemberSanders,

RankingMemberPallone,andRankingMemberBoyle:

Asyourequested,thisletterprovidesinformationabouthowchangesto

fundingfortheNationalInstitutesofHealth(NIH)andchangesintheFood

andDrugAdministration’s(FDA’s)reviewtimeswouldaffectthe

developmentofnewdrugs.Inparticular,youaskedtheCongressional

BudgetOfficetoassesstwohypotheticalscenarios:

•Apermanent10percentreductionintheamountoffundingthatthe

governmentprovidestotheNIH,and

•Anine-monthincreaseinthetimeittakestheFDAtoreviewnew

drugapplications(NDAs).

Toassesstheeffectsofthe