牙龈卟啉单胞菌与不良妊娠结局的相关研究进展.pdfVIP

麵〇麵户咖和《仏）是一种革兰阴性厌氧菌，是牙周炎尤其是慢性牙周炎病变区

Por/Ayr,.

或活动部位最主要的病原菌。研究表明，牙周炎与多种不良妊娠结局（adversepregnancyoutcomes,AP0)有关，这一过程涉及

多种病理生理机制，而P.扣以m仏作为关键牙周致病菌之一在其中扮演重要角色。目前我们对P.扣#m仏与AP0的关系及

其作用机制的认识仍然十分有限。该文拟通过回顾近年来发现的仏与AP0之间相关的直接或间接的证据，对A

咖afe与AP0的联系和作用机制作一综述。

[关键词]牙周炎牙周致病菌牙龈卟啉单胞菌;不良妊娠结局

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[中图分类号]R781.42[文献标识码]A[文章编号]1003-9872(2021)03-0265-04

[doi]10.13591/ki.kqyx.2021.03.014

ProgressofresearchoncorrelationsbetweenPorphyromonasgingivalisandadversepregnancyoutcomes

QIShuai,LINXiaoping.(DepartmentofStomatology,ShengjingHospitalofChinaMedicalUniversity,Shenyang110004,China)

Abstract：Porphyromonasgingivalis(P.gingivalis)

isagram-negativeanaerobicbacterium,whichisthemainpathogenofperiodon­

titis,especiallychronicperiodontitis.Studieshaveshownthatperiodontitisisrelatedtoadversepregnancyoutcomes(APO).This

P.gingivalis,

processinvolvesavarietyofpathophysiologicalmechanisms,andasoneofthekeyperiodontalpathogens,playsanimpor­

P.gingivalis

tantroleintheprocess.Atpresent,ourunderstandingoftherelationshipbetweenandAPOanditsmechanismofinterac­

P.gingivalis

tionisstilllimited.ThispaperintendstoreviewthedirectorindirectevidenceoftherelationshipbetweenandAPOinre-

P.gingivalis

centyears,andtomakeareviewoftherelationshipandmechanismof