脑外伤开颅术后颅内感染发生的危险因素分析.pdfVIP

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脑外伤开颅术后颅内感染发生的危险因素分析

杨宏建石强杨云峰晏桢

614000武警四川省总队医院神经外科

doi:10.3969/j.issn.1007-614x.2019.08.055

摘要目的：探讨脑外伤开颅术后颅内感染发生的危险因素。方法：收治开颅手术脑外伤患者100例，分研究组(开

颅术后发生颅内感染)和对照组(开颅术后未发生颅内感染)。分析研究组开颅术后发生颅内感染的相关因素。结果：研

究组和对照组在年龄、术前GCS评分＜8分、手术时间、脑脊液瘘、术后低蛋白、择期手术上差异有统计学意义(P＜

0.05)；年龄、术前GCS评分＜8分、手术时间、脑脊液瘘、术后低蛋白、择期手术为发生颅内感染的高危因素。结论：

脑外伤开颅术后发生颅内感染的危险因素有高龄、低GCS评分、手术时间延长、脑脊液瘘、术后低蛋白及择期手术。

关键词脑外伤；开颅；颅内感染

Riskfactorsforintracranialinfectionaftercraniotomyinpatientswithtraumaticbraininjury

YangHongjian,ShiQiang,YangYunfeng,YanZhen

DepartmentofNeurosurgery,SichuanProvincialGeneralHospitalofArmedPoliceForce614000

AbstractObjective:Toexploretheriskfactorsofintracranialinfectionaftercraniotomy.Methods:100patientswithtraumatic

braininjuryaftercraniotomywereselected,theyweredividedintothetwogroups:thestudygroup(intracranialinfectionoccurred

aftercraniotomy)andthecontrolgroup(nointracranialinfectionoccurredaftercraniotomy).Therelatedfactorsofintracranial

infectionaftercraniotomywereanalyzed.Results:Thereweresignificantdifferencesinage,preoperativeGCSscore＜8,operation

time,cerebrospinalfluidfistula,postoperativelowproteinandselectiveoperationbetweenthestudygroupandthecontrol

group(P＜0.05).Age,preoperativeGCSscore＜8,operationtime,cerebrospinalfluidfistula,postoperativelowproteinandselective

operationwerethehighincidenceofintracranialinfectiondangerousfactors.Conclusion:Theriskfactorsofintracranialinfection

aftercraniotomyfortraumaticbraininjuryareoldage,lowGCSscore,prolongedoperationtime,cerebrospinalfluidfistula,

postoperativelowproteinandselectiveoperation.

KeywordsTraumaticbraininjury;Craniotomy;Intracranialinfection

脑外伤是神经外科的危重疾病，多15.22)岁。对照组男25例，女25例；年龄GCS评分＜8分、手术时间、脑脊液瘘、

需要采取开颅术治疗。相关研究指出开