HIV口腔表征教学教材.ppt

The last one of viral infection , Hairy Leukoplakia ，the most likely cause is Epstein Barr virus (EBV)?. It can be asymptomatic（无症状的）,or manifests as nonmovable , white, vertical, corrugated（褶皱的）lesion. on the lateral margins of the tongue （舌侧缘?。 The creamy white plaques of pseudomembranous candidiasis are removable; the white lesions of hairy leukoplakia are nonremovable. * Mild Hairy leukoplakia * Extensive hairy leukoplakia 主要依据临床表现,毛状白斑的 组织学改变有时和其他白斑相似,无论从组织学和 临床来看,毛状白斑没有特异性的改变。如果初步 印象为毛状白斑,可检查是否存在EB病毒来进一 步确定诊断。检测EB病毒可用免疫细胞化学技 术、组织原位杂交、非侵袭性原位杂交技术,或用电 子显微镜观察。 * Normally, Treatment is not required, it will get improved with antiretroviral therapy?for HIV. My?part?is?done 。Now ，Let‘s welcome chenyangxia to do her part。 * Oral Manifestations of HIVHIV口腔表征 Oral Manifestations of HIV HIV口腔表征 Significance HIV口腔表征的意义 HIV口腔表征的分类 Classification Management HIV口腔表征的治疗 ?Early clinical features of HIV infection Greenspan JS, et al. Oral Surg Oral Med Oral Pathol 1992;73:142-4. Agbelusi GA，et.al. Oral Dis; 11: 370-373 感染HIV病毒的早期临床表现 90% of HIV patients ≥ 1 oral manifestation Strong indication of the presence of HIV infection Markers for immune deterioration, disease progression, prognosis 90%以上HIV患者≥一个口腔表征 口腔表征强烈提示感染了HIV 免疫受损和疾病进展、预后差的标志 Significance of oral lesions of HIV classification clinical features Diagnosis Treatment FUNGAL LESIONS VIRAL LESIONS BACTERIAL LESIONS NEOPLASTIC LESIONS Others Candidiasis（念珠菌病） Most common intra-oral lesion 最常见的口腔内皮损 Pathogen：? Candida albicans 白色念珠菌 Non-albicans species 非白色念珠菌 Four types： Pseudomembraneous candidiasis ：55~70% 伪膜性念珠菌病 Erythematous candidiasis ：26~50% 红斑性念珠菌病 Angular cheilitis ： 0~1.7% 口角炎 Hyperplastic candidiasis 0~1% 增殖性念珠菌病 Candidiasis（念珠菌病） clinical features classification Treatment FUNGAL LESIONS VIRAL LESIONS BACTERIAL LESION