正清风痛宁治疗骨关节炎的疗效及副作用 - 道客巴巴.docxVIP

?88 ?88 ? 陶细较等.桂基底动畝供血不足性眩晕BAEP檢査结果分析 ? ? 86 ? 胡水红尋.正清风痛宇治疗骨关节炎的疗效及剖作用 第 16#m2M2001年 第 16#m2M 2001年6月 中国康與 Zhongguo Kaogfu Vol. 16 No. 2 June. 2001 ? 85 ? 正清风痛宁治疗骨关节炎的疗效及副作用 胡永红赖先阳洽胜豪刘沛嫁 摘要：目的观察正清风痛宁对骨关节災（OA）的疗效及氯苯毗胺能否作为正清风痛宁的协同药同时眼用M减轻 其组胺泽放所致的剧作用.方法60例患者分为AB2组，A组服正清风痛宁60 mg. 1日3次，眼4局，氯苯毗胺 4 mg.l 0 3次，第1, 2周脳.B组眼正清风痛宁60 nig, 1 Q 3次.眼4周.结黒经过4周治疗.2组各項观测指 标均改善、治疗前后差异有显着性、均PV0.001. A组加服氯苯毗胺其不良反应发生率及程度皆低于B组，但2组 统什分析差异无显蕃性.正清风痛宁怡疗OA疗效显著?氯苯毗胺虽能改善皮肤症状，但对头及胃痛改善不明显、并 岀现U干和嗜睡副作用.结论氯苯毗胺为H,受体阻滞剂，对Hz受体无作用，所以在使用正清风羸宁时不必倉規加 眼氯苯毗胺之类的组胺拮抗剂。 关?词；骨关节炎,电医药疗法正清风痛宁4副作用 中图法分类号厂R593.21文献标识码；A 文章编号:1001-2001 （2001） 02-0085-03 Therapeutic Effects and Side Effects of Zhengqlngfengtongrdng in the Treatment of Osteoarthritis Hu Yonghong, Nai Xaonyangt Tu Shenghao ? et al. Tangji Hospital w Tongji Medical College ? Huazhong University of Science and Technology ? Wuhan 430030 Abstract： Objective To observe the therapeutic effects of Zhengqingfengtongning (ZQFTN) in the treatment of osteoarthritis (OA) ^nd (he synergic action of chlortrimeton to reduce the histamine-induced sede effects. Methods Sixty patients with OA were divided into group A (orally taking ZQFTN 60 mg, t. i? d for 4 weeks? chlortrimeton 4 mg* t. L d. on the first and second week) and group B (orally taking ZQFTN 60 mg. t. i. d for 4 weeks). Results After 4 week treatment? the various parameters in the two groups were all improved significantly (both P 0? 001 )? The occurrence of side effects in the group A was lower and severity milder than in the group B (P0? 05). ZQFTN had a prominent efficacy for OA? Chlortrimeton could improve skin symptoms ■ but it could not obviously improve the headache and stomach pain and the side effects such as xerostomia and lethargy occurred? Conclusion It was not necessary to routinely take chlortrimeton during the administration of ZQFTN? Key words? osteoarthritis^ Chinese traditionftl treatment) Zhengqingfengtongningi therapy 正清风痛宁是有效的抗风湿药.能治疗各种风 湿病，但对骨关节炎（Ostcoarthrisis, OA）的报道 甚少，本文目的之一旨在观察其