妊娠期糖代谢异常对母婴结局的影响.docVIP

妊娠期糖代谢异常对母婴结局的影响 冯浩华（广东省鹤山市人民医院妇产科，广东鹤山529700） 【摘要】目的：探讨妊娠期糖代谢异常对母婴的影响。方法：回顾分析我院2009年1月-12月住院分娩妊娠期糖代谢异常经饮食营养治疗或胰岛素治疗血糖控制良好88例（观察组）与同期诊断妊娠期糖代谢异常未经饮食营养治疗或经治疗但血糖控制效果不佳51例（对照组），比较两组妊娠结局。结果：对照组孕妇剖宫产、妊娠期高血压疾病、羊水过多、巨大儿、胎膜早破、新生儿低血糖发生率显著高于观察组。结论：妊娠期糖代谢异常对孕产妇及围生儿预后有不良影响，对孕妇中孕期进行妊娠期糖尿病筛查，若发现妊娠期糖代谢异常孕妇应进行积极干预。 【关键词】妊娠糖代谢异常 母儿预后 Analysis on 139 maternal and fetal with gestational abnormal glucose metabolism 【Abstract】Objective: To investigate the effect of abnormal glucose metabolism during pregnancy on maternal and fetal outcomes. Methods: We study the 139 patients with gestational abnormal glucose metabolism in our hospital during 2009. They are divided into two groups: treatment group with 88 patients, whose blood glucose are well controlled by diet or insulin treatment; control group with 51 patients, who have not been treated or with no significant treatment effects. We then compared the outcomes of these two groups. Results: The incidences of cesarean section，pregnancy- induced hypertension，polyhydramnios，fatal macrosomia，premature rupture of membrane，neonatal hypoglycemia in the treatment group were all higher those in the the control group, and all results are statistically significant. . Conclusion: Abnormal glucose metabolism during pregnancy can produce negative effects on mothers and neonates. We should carry out diabetes screening on the pregnant women, and effective intervene those patients with abnormal glucose metabolism during pregnancy. positive treatment the pregnant women of 【Key words】Abnormal Glucose Metabolism Maternal and Fetal Outcomes 妊娠期糖代谢异常包括妊娠期糖尿病（GDM）及妊娠期糖耐量异常(GIGT)。我国平均发病率为6.6%1。近年来，呈逐年明显升高趋势。妊娠期糖代谢异常在围生期可引起严重母婴并发症，如：妊娠期高血压疾病，巨大儿，羊水过多，胎膜早破，新生儿低血糖的发生率均增高，如对此处理不当，将对围生期母婴产生巨大危害。 1资料和方法 1.1一般资料 2009年1月至12月在我院住院分娩，妊娠期糖代谢异常139例，年龄20-43岁，平均年龄28.6岁，其中初产妇78例，经产妇61例。其中门诊或入院后诊断为妊娠期糖代谢异常经饮食营养治疗或饮食营养加胰岛素治疗血糖控制良好88例，作为观察组。同期诊断妊娠期糖代谢异常未经饮食营养治疗或经治疗但血糖控制效果不佳51例作为对照组。2组孕妇的孕周、年龄、孕产次相比无显著性差异，具有可比性。 1.2方法 密切监测本组孕妇从入院到现在的各个时期血糖的含量，并且及时做好记录。中发现孕妇血糖含量不在正常范围内则通