Childhood obesity public-health crisis, common sense cure 儿童肥胖：公共卫生危 机，常识治疗.pdfVIP

SEMINAR Seminar Childhood obesity: public-health crisis, common sense cure Cara B Ebbeling, Dorota B Pawlak, David S Ludwig During the past two decades, the prevalence of obesity in children has risen greatly worldwide. Obesity in childhood causes a wide range of serious complications, and increases the risk of premature illness and death later in life, raising public-health concerns. Results of research have provided new insights into the physiological basis of bodyweight regulation. However, treatment for childhood obesity remains largely ineffective. In view of its rapid development in genetically stable populations, the childhood obesity epidemic can be primarily attributed to adverse environmental factors for which straightforward, if politically difficult, solutions exist. Historically, a fat child meant a healthy child, one Complications of childhood obesity who was likely to survive the rigors of undernourishment Childhood obesity is a multisystem disease with and infection. In the past decade, however, excessive potentially devastating consequences (figure 2).16–40 fatness has arguably become the primary childhood Several complications warrant special attention. health problem in developed nations and, to some As with adults, obesity in childhood causes degree, in other parts of the world. Here we review the hypertension, dyslipidaemia, chronic inflammation, scope of the problem and discuss developments in increased blood clotting tendency, endothelial establishment of cause, prevention, and treatment of