实验诊断学脑脊液检查教学课件.ppt

We all known that bilirubin is transformed from hemoglobin, so when the brain hemorrhage is occur ,the RBC will be destroyed in the CSF (because the osmotic pressure is different from serum to CSF). Of course , it need 12h to finish these transformation. may persist for up to three weeks If the hemorrhage is occurred only several hours, Xanthochromia wont occur. Increased serum bilirubin,because the uncombined bilirubin can cross the BBB. It also can be seen in any condition where CSF protein is very high and in patients with jaundice. The white cell count is increased when there is inflammation of the central nervous system, particularly the meninges.Bacterial infections (eg, meningitis, cerebral abscess, early tuberculous meningitis, septicaemia) are usually associated with the presence of neutrophils in the CSF. usually associated with the presence of Ne in the CSF, because bacteria can cause WBC increase highly. The white cell count is increased when there is inflammation of the central nervous system, particularly the meninges.Bacterial infections (eg, meningitis, cerebral abscess, early tuberculous meningitis, septicaemia) are usually associated with the presence of neutrophils in the CSF. purulent meningitis，WBC↑↑－－－－the number of WBC increased highly tuberculous meningitis，WBC↑------------ the number of WBC increased only a bit So if you find that the CSF sample which you collected from your patient is turbid , there must be something in it. Maybe are WBCS, maybe are protein, or bacter,fungers. 结核杆菌：tubercle bacillus; ↑↑---highly The pellicle is contain plenty of tubercle bacillus, and we can catch this pellicle for TB culture or make smear, its positive rate is more higher than we use the CSF sample. The bacterium will decomposing the glucose into acid , cause the PH decreasing The lactic acid increasing in our muscle cause our leg ache Increased PH value is caused by the increasing of acid substance,such as LA, which is produced a