病毒性肝炎1---副本.ppt

“两对半”分析举例 HBsAg 抗-HBs HBeAg 抗-HBe 抗-HBc ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ HBsAg 抗-HBs HBeAg 抗-HBe 抗-HBc ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ＋ ①窗口期，抗-HBs即将出现；②HBV感染已过 * Key messages Hepatitis B is one of the most common infectious diseases in the world. There are 350 million chronic carriers of the hepatitis B virus worldwide. Hepatitis B is the ninth leading cause of death worldwide. Geographical prevalence varies widely throughout the world. Nearly 75% of HBV chronic carriers are Asian. Points of explanation The geographical prevalence of hepatitis B varies from a highly endemic disease in Asia and Africa to a disease of low prevalence in North America and Western Europe. Additional information More than 2 billion people worldwide have been infected with HBV though not all of these have become chronically infected. The majority of hepatocellular carcinoma in Asia results from hepatitis B virus infection References Margolis HS, Alter JH, Habler SC. Hepatitis B: evolving epidemiology and implications for control. Sem Liver Dis 1991;11:84-92 Mast EE, Alter JH. Epidemology of viral hepatitis: an overview. Sem Viral 1993;4:273-283 World Health Organisation Data * 病 毒 性 肝 炎 肝炎，是指一类由各种病因引起的肝脏炎症病变。 其病因复杂多样： 病毒性肝炎 酒精性肝病 脂肪肝：临床十分常见 药物性肝炎：抗痨或抗菌药、免疫抑