MRI及WI在新生儿低血糖脑损伤中的应用.docVIP

MRI及DWI在新生儿低血糖脑损伤中的应用 郭庆清许祖梅李梅芳 (莆田学院附属医院医学影像科351100) 】目的探讨新生儿低血糖脑损伤的MRI特征及扩散加权成像 (DWI)在低血糖脑损伤诊断中的应用价值。方法回顾性分析9例经临床确诊的 新生儿低血糖脑损伤病例的MRI资料,所有病例均在出生后1?7d行MRI检查， 扫描序列包括常规T1WI、T2WI及DWI序列。结果9例患儿血糖水平在0.2? 1.8mmol/l，平均约0.95mmol/l。常规T1WI表现为受累部位稍低信号4例，稍高 信号1例；7例T2WI表现为受累部位稍高信号或灰白质分界不清。9例行DWI 扫描均发现斑片状、条状及脑回样高信号，其中受累部位双侧顶枕叶皮层及皮层 下白质8例，胼胝体受累5例，侧脑室旁脑白质受累4例，基底核受累2例，尾 状核头部受累1例，所有患儿小脑及脑干均未见异常。结论新生儿低血糖脑损 伤以双侧枕顶叶后部脑组织及胼胝体压部最常受累，常对称性分布，具有一定特 征性。DWI序列较常规T1WI及T2WI序列在低血糖脑损伤的诊断及评估上更其 优越性。 关键词】低血糖症脑损伤新生儿磁共振成像 】R445 】A 】2095-1752 (2014) 07-0061-02 The value of MRI and DWI in the diagnosis of neonatal hypoglycemic brain injury Guo Qingqing, XU Zumei, LI Meifang Department of Medical Imaging, The Affiliated Hospital of Putian University, Putian 351100 Abstract】 Objective： To investigate MRI features of neonatal hypoglycemic brain injury(NHBI)and to explore the value of diffusion-weighted imaging (DWI)in the diagnosis of NHBI. Methods： MR imaging features of 9 neonates with NHBI were retrospectively evaluated. All the neoates were performed 1 ?7 days of life with MRI sequences including TlWh T2WI and DWI. Results： The level of blood glucose was 0.2?1.8mmol / I in 9 cases of neonatal hypoglycemia，an average about 0.95mmol / 1. NHBI showed slight hypointensity(4 cases)and slight hyperintensity(l cases)on TIWI and hyperintense(7cases)and poor gray-white differentiation on T2WI. All of the DWI imaging showed abnormalities； The parietal and occipital cortex and subcortical white matter abnornlalities occurred in 88.9% (8cases) of infants with hypoglycemia brain injury, corpus callosum abnormalities occurred in 55.6%(5cases)of intants with hypoglycemia brain injury;the periventricular white matter injury occurred in 44.4%(4cases)of infants with hypoglycemia brain injury;22.2%(2cases)ofinfants with hypoglycemia had basal ganglia abnormalities,and 11.1% (lcase)had head of caudate nucleus abmormality. There were no abnormal signal in cerebellum and brain stem in all cases.Conclusion： NHBI has