从PRKAG3基因筛选与运动能力相关基因指标研究-体育教育训练学专业论文.docx

relative value between different genotypes have significantly different trend, with the GG genotype were higher than that with the A-type person. ③Significantly higher than in the frequency domain HRV-related indicators, the male athlete Pro71Ala sites in heart rate variability (HRV) among different genotypes quiet state of total power (TP) showed a statistically significant difference, namely those with the CC genotype carrying (CG + GG) type person. Conclusions: PRKAG3 gene locus rs6436094 GG genotype were carrying and Pro71Ala sites carrying the CC genotype may be able to use genetic markers as an athlete selection, but the need to increase the sample size is further argued. Keywords: PRKAG3 gene; monocytes Xi acid polymorphism; athletic ability 目 录 摘 要 ............................................................ I Abstract ......................................................... II HYPERLINK \l _bookmark0 目 录 ......................................................... IV HYPERLINK \l _bookmark1 前 言 ............................................................. 1 HYPERLINK \l _bookmark2 第一部分 文献综述 ................................................ 4 HYPERLINK \l _bookmark3 PRKAG3 基因概述 4 HYPERLINK \l _bookmark4 1.1.1 PRKAG3 结构和活性 4 HYPERLINK \l _bookmark5 1.1.2 组织特异性表达.........................................5 HYPERLINK \l _bookmark6 1.1.3 PRKAG3 的生理作用 5 HYPERLINK \l _bookmark7 PRKAG3 与运动 6 HYPERLINK \l _bookmark8 1.2.1 运动影响 PRKAG3 基因表达 6 HYPERLINK \l _bookmark9 1.2.2 运动中 PRKAG3 基因的表达量与肌纤维类型 6 HYPERLINK \l _bookmark10 1.2.3 PRKAG3 调节运动能量代谢 7 HYPERLINK \l _bookmark11 PRKAG3 对糖代谢的调节 8 HYPERLINK \l _bookmark12 PRKAG3 对脂代谢的调节 8 HYPERLINK \l _bookmark13 1.3 PRKAG3 基因多态性的研究现状 9 HYPERLINK \l _bookmark14 1.4 展望 ........................................................9 HYPERLINK \l _bookmark15 第二部分 PRKAG3 基因与运动能力的实验研究 11 HYPERLINK \l _bookmark16 研究一：PRKAG3 基因位点运动员组与对照组中的分子特征 11 HYPERLINK \l _bookmark17 1 实验总体设计 ..............................................