糖化血红蛋白及血糖水平在急性心肌梗死行PCI术患者的预后中的应用价值分析.docVIP

糖化血红蛋白及血糖水平在急性心肌梗死行PCI术患者的预后中的应用价值分析 　　[摘要] 目的 研究糖化血红蛋白（HbA1c）与血糖水平在急性心肌梗死患者行经皮冠状动脉介入治疗（PCI）的预后价值。 方法 选择2012月1月～2013年12月在河北省沧州市人民医院接受接受PCI术治疗的急性心肌梗死患者125例。根据HbA1c以及餐后2 h血糖水平将其分为观察组（HbA1c6.5%）67例和对照组（HbA1c≤6.5%）58例；对比两组患者临床患病情况、HbA1c等水平、治疗后心血不良事件发生以及LVDd、LVEF水平。 结果 观察组糖尿病、多支动脉病变以及陈旧性心肌梗死患者的比例显著高于对照组；观察组HbA1c、餐后2 h血糖、TG水平均显著高于对照组；观察组治疗后再发心肌梗死、心源性休克以及频发室性期前收缩发生比例显著高于对照组；观察组治疗后3个月LVDd高于对照组，而LVEF水平低于对照组；差异均有统计学意义（均P 0.05）。 结论 急性心肌梗死患者行PCI术时HbA1c与血糖水平偏高容易升高心血管事件的发生率，同时并发糖尿病、多支动脉病变的概率更大。临床上采用HbA1c与血糖水平具有较高的预后价值，值得推广应用。 　　[关键词] 急性心肌梗死；皮冠状动脉介入术；糖化血红蛋白；血糖水平；预后价值 　　[中图分类号] R542.2 [文献标识码] A [文章编号] 1673-7210（2016）02（b）-0063-04 　　Application value of glycosylated hemoglobin and blood glucose levels in patients with acute myocardial infarction undergoing PCI 　　ZHAO Zhijie1 YAN Yafang2 　　1.Department of Laboratory， Cangzhou Peoples Hospital， Hebei Province， Cangzhou 061000， China； 2.Electrocardiogram Room， Cangzhou Peoples Hospital， Hebei Province， Cangzhou 061000， China 　　[Abstract] Objective To explore the prognostic value of HbA1c and blood glucose levels in patients with acute myocardial infarction （AMI） by percutaneous coronary intervention （PCI）. Methods 125 patients with acute myocardial infarction treated by PCI from January 2012 to December 2013 in Cangzhou Peoples Hospital were selected from patients with acute myocardial infarction. According to the HbA1c and postprandial 2 h blood glucose levels， 125 patients were divided into the observation group （HbA1c 6.5%） of 67 cases in control group （HbA1c of 6.5% or less） 58 cases； The clinical prevalence， HbA1c and LVEF and LVDd levels were compared between two groups. Results The proportion of patients with diabetes， multiple arterial diseases and old myocardial infarction in the observation group were significantly higher than those in the control group. The levels of HbA1c， postprandial 2 h blood glucose and TG in the observation group were significantly higher than those in the control group. The observation group