专项整治前后心外科Ⅰ类口围术期抗菌药物预防性使用分析.docVIP

专项整治前后心外科Ⅰ类切口围术期抗菌药物预防性使用分析 　　摘 要 目的：探讨抗菌药物专项整治活动对我院心外科Ⅰ类切口手术围术期预防性应用抗菌药物的影响。方法：随机抽取整治前后Ⅰ类切口手术病例各200份，对围术期抗菌药物预防使用的情况进行统计分析。?Y果：抗菌药物专项整治后，围术期抗菌药物预防应用的合理性明显提高，头孢呋辛使用比例由整治前的2.5%上升至89.0%；术前0.5～1 h给予抗菌药物的比例由63.5%上升至100.0%；用药疗程在48～72 h的比例由4.5%提高至50.5%；围术期无联合用药的情况，术后感染率由19.5%降至8.5%。结论：我院开展的抗菌药物专项整治活动效果显著，对围术期抗菌药物的合理使用起到了积极的促进作用。 中国论文网 /6/viewhtm　　关键词 抗菌药物 围手术期 专项整治 合理用药 　　中图分类号：R969.3； R197.1 文献标志码：C 文章编号：1006-1533（2018）07-0056-03 　　Analysis of antibiotic prophylaxis for type I incision of cardiac operation during perioperative period before and after special rectification* 　　GUO Liping**， YU Li， YUAN Dongdong** 　　（Department of Pharmacy， the Seventh People’s Hospital of Zhengzhou， Zhengzhou 450016， China） 　　ABSTRACT Objective： To discuss the effect of antibiotics prophylaxis for type I incision of cardiac operations during perioperative period before and after the special rectification of antibiotic use. Methods： Two hundred cases each before and after the rectification were randomly selected. The preventive use of antibiotics during perioperative period was statistically analyzed. Results： The rational use of antibiotics as prophylaxis was significantly improved after rectification. The ratio of the utilization of cefuroxime was increased from 2.5% to 89.0%， the proportion of the application of antibiotics within 0.5～1 h before operation was increased from 63.5% to 100.0%， and the proportion of medication course in 48～72 h was increased from 4.5% to 50.5%. The combinatory use of antibiotics was completely eradicated and the incidence of postoperative infection was decreased from 19.5% to 8.5%. Conclusion： The effect of the special rectification of antibiotic use is remarkable， which plays a positive role in promoting the rational use of antibiotics during perioperative period. 　　KEy WORDS antibiotics； perioperative period； special rectification； rational drug use 　　心血管外科手术时间长、创伤大，手术通常伴有异物植入，污染机会大大增加，一旦发生手术部位切口感染后果尤为严重，不仅延长患者住院时间、增加患者的住院费用，而且也会极大地增高患者死亡率[1-2]。