联萘基单齿磷配体不对称氢化研究进展课件.ppt

联萘基单齿磷配体不对称氢化研究进展;内容简介;手性工业的税收总额增长趋势及预测;2001年诺贝尔化学奖－不对称合成;不对称氢化中常用的双磷配体;联萘基单齿磷配体的发展;联萘基单磷配体在烯烃不对称氢化中的应用;J. Am. Chem. Soc. 2000, 122, 11539;金属/配体、底物、压力;(S)-a (S)-b (S)-c (S)-d (S)-e (S)-f;2 3 4 5 6;Why Are BINOL-Based Monophosphites Such Efficient Ligands in Rh-Catalyzed Asymmetric Olefin Hydrogenation;Rh/ligand ratio of 1:2 is optimal;Why Are BINOL-Based Monophosphites Such Efficient Ligands in Rh-Catalyzed Asymmetric Olefin Hydrogenation;Why Are BINOL-Based Monophosphites Such Efficient Ligands in Rh-Catalyzed Asymmetric Olefin Hydrogenation;Zheng Z, et al., Org. Lett. 2003, 5, 4137 Zheng Z, et al., J. Org. Chem. 2004, 69, 2355 Zheng Z, et al., Tetrahedron: Asymmetry 2004, 15, 2011;“Nothing comes without a hidden cost or flip side.” “Asymmetric catalysis is a great boon but carries with it the problem of having to deal with residual metals.”;固载化：聚合物;Tetrahedron Lett., 2006, 47, 4263;固载化：AlTUD-1;Chem. Commun., 2004,?24,2830 ;固载化:介孔材料;;前景展望;参考文献;Thank You;Nonlinear effects;Chem. Commun., 2000, 961;Asymmetric Conjugate Addition