A Low Cost Optical Cherence Tomography Machine一种低成本的光学相干断层扫描机器.docVIP

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A Low Cost Optical Cherence Tomography Machine一种低成本的光学相干断层扫描机器.doc

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A Low Cost Optical Cherence Tomography Machine一种低成本的光学相干断层扫描机器

A Low Cost Optical Coherence Tomography Machine Kevin White ksw18@ EBME 105: Introduction to Biomedical Engineering Tim Buetler tmb23@ 10/31/2010 Introduction: Optical Coherence Tomography (OCT) is an emerging non-invasive imaging technique with state of the art designs reaching sub micrometer resolutions (1). While technology is beginning to become widely accepted and used in the developed world, it is out of reach for many third-world countries because it is too expensive for the poorer nations of the world. The goal of this project is to vastly reduce the cost of this technology for glaucoma screening in poorer nations. This project aims to reduce the cost of this OCT machine to $4,000-$6,000 while designing the machine to be relatively small and portable. OCT is based on the principles of low-coherence interferometry and often employs a Michelson interferometer (2). An interferometer is a device which utilizes lights phase properties to compare the light that returns from two mirrors; one mirror a known distance from the receptor and another mirror an unknown distance. The unknown distance can be calculated by comparing the phases of the light from the unknown length and the light at a known length (2). In a basic OCT set-up a light source emits a broadband spectrum of light which is carried over fiber optic cable to an evanescent mode coupler. The coupler divides the light evenly, with half of the light directed toward the reference arm and the other half directed to the sample which is to be scanned. The light is reflected back from both the reference arm and the scanning sample and is recorded by a photoreceptor. The data is then translated in a digital signal, processed, displayed by a computer (2). Since OCT has become a more popular imaging modality, different engineers have tried to eliminate some of the drawback typically associated with OCT such as low scan speed and lack of portability. These different designs have altered some of the bas