颅内出血性病灶MRI扫描序列优选研究.docVIP

颅内出血性病灶MRI扫描序列优选研究 　　[摘要] 目的：探讨MR各序列成像在脑出血性病变的敏感性。方法：回顾性分析100例脑出血患者常规自旋回波(SE)T1WI、快速自旋回波(TSE)T2WI、液体衰减反转恢复序列(FLAIR)、扩散加权成像(DWI)和小角度激发快速梯度回波序列(T2-FFE)资料，比较SE-EPI、T2-FFE序列脑出血病灶的显示率，分析其信号特征，并探讨SE-EPI代替T2-FFE的可行性。结果：T2-FFE为显示脑出血性病灶最敏感的序列，能显示常规序列所不能显示的微出血。无论在检出脑出血灶，还是图像对比度，SE-EPI均远低于T2-FFE。结论：T2-FFE序列能提高脑出血病灶的检出数及早期诊断率，应作为常规扫描序列；在临床脑出血筛选方面，SE-EPI无法代替T2-FFE。 　　[关键词] 磁共振成像；梯度回波序列；弥散加权成像；出血性病变 　　[中图分类号]R445 [文献标识码]B [文章编号]1673-7210（2008）05（c）-084-02 　　 　　The optional MRI sequences in intracranial hemorrhagic lessons 　　FAN Yuan-xian, CHENG Chuan-hu, HUANG Yao-sheng 　　（Department of Radiology, Huizhou Central Peaples Hospital, Huizhou 516001, China） 　　[Abstract] Objective:To evaluate the most sensitive MR sequences in the detection and diagnosis of the intracranial hemorrhagic lessons.Methods:Retrospectively, 100 cases with intracranial hemorrhagic lessons were performed with MRI routine scan、FLAIR、DWI and T2-FFE sequences. The sensitivity of SE-EPI and T2-FFE in the hemorrhagic lessons was compared to determine whether the EPI sequences can be used as an alternative to the GRE sequence for detection of chronic hemorrhage. Results:T2-FFE was the most sensitive sequence in the detection of intracranial hemorrhagic lessons. T2-FFE could detect microbleeds which couldnt be displayed in the routine sequence, such as T1WI, T2WI, FLAIR. Compared to SE-EPI, T2-FFE had a better sensitivity, and the figure contrast was better also. Conclusion:T2-FFE sequence played an important role in the detection and diagnosis of intracranial hemorrhagic diseases, which made it necessary for the clinical MR examinations. And SE-EPI could not use to replace T2-FFE in the detection of hemorrhagic lessons, especially microbleeds. 　　[Key words] MRI;T2-FFE;Diffusion-Weighted imaging;Hemorrhagic lessons 　　 　　脑出血的病因多种多样，如外伤、高血压性出血、出血性梗死、脑肿瘤卒中、动脉瘤破裂出血、血管畸形出血，以及脑血管病等。脑出血的检出，对临床诊断以及治疗方式的选择意义重大[1]。以往脑出血的诊断多依赖于CT，随着MRI软硬件的发展及临床相关研究的深入，MRI在脑出血的检出、病因诊断中已取代CT，成为首选检查方式。T2加权梯度回波序列（T2-FFE）远较常规自旋回波（SE）、快速