清热活血泻浊汤治疗湿热瘀结型多囊卵巢综合征的临床研究汇总.pdfVIP

摘 要 目的：本文通过运用清热活血泻浊汤治疗湿热瘀结型多囊卵巢综合征（PCOS）,观察 其临床疗效，并初步探讨其作用机理，为进一步拓展PCOS 的中医药治疗方法提供依 据。 方法：选取湿热瘀结型PCOS 患者共108例，随机分为三组，各为36 例：A 组（治疗 组）、B 组（中药对照组）、C 组（西药对照组）。治疗组运用清热活血泻浊汤内服，中 药对照组采用龙胆泻肝汤内服，治疗三个月。西药对照组选用达英-35 口服，治疗三 个月经周期。对其月经周期及全身伴随症状、多毛、痤疮变化的量化积分；性激素、 B 超监测卵巢体积大小及小卵泡个数的变化进行统计分析。 结果：治疗组总有效率为80.0%，痊愈率为22.9%；中药对照组总有效率为67.6%， 痊愈率为14.7%；西药对照组总有效率为88.6%，痊愈率为25.7%。通过治疗后比较 发现，治疗组和西药对照组对患者月经周期及全身伴随症状、多毛、痤疮、性激素， 卵巢体积及小卵泡个数均有改善(P0.05)。中药对照组对患者痤疮、卵巢体积的改善 不明显(P0.05)。治疗组的总体疗效和痊愈率明显高于中药对照组，低于西药对照组 （P0.05），在中医伴随症状的改善方面优于中药对照组和西药对照组(P0.05)；随 访中治疗组和中药对照组的复发率和副作用均小于西药对照组，治疗组比中药对照组 表现更明显。 结论：清热活血泻浊汤不仅能显著改善湿热瘀结型PCOS 患者的月经及伴随症状，且 对多毛、痤疮等症的改善尤为明显；对PCOS 患者的性激素水平和卵巢体积及小卵泡 个数也能明显改善；还可有效降低复发率。本研究初步证实清热活血泻浊汤内服是治 疗湿热瘀结型PCOS 的有效方法，值得进一步深入研究。 关键词：多囊卵巢综合征;湿热瘀结型;清热活血泻浊汤 The Clinical Research on the Effect of Heat-cleaning Blood-activating Turbidity- purgation Soup on Accumulation of Sthenia-heat type of PCOS Abstract Objective: Through the treatment of heat-cleaning blood-activating turbidity- purgation soup on the accumulation of sthenia-heat type of polycystic ovary syndrome(PCOS), this paper observes the improvement of their menstruation and systemic symptoms, obesity ,hair, acne of the patients with PCOS , and discusses the mechanism of the curative effect of treatment of polycystic ovary syndrome(PCOS),which also provides the scientific basis for other aspects of clinical and experimental research. Methods : We select a total of 108 patients with accumulation of sthenia-heat type of PCOS and divide them into three groups randomly, each for 36 cases: group A (treatment group), group B (Chinese traditional medicine control group), group C (western medicine control group). We take one month as a treatment course, observe the patients for three menstrual cycles, and collect the data of the change of their menstruation and systemic sympto