高通量透析对维持性血液透析患者血液生化指标的影响.docVIP

精品论文 参考文献 高通量透析对维持性血液透析患者血液生化指标的影响 谢鸣部 潘淼（通讯作者） 黄智敏 （福建宁德市医院肾内科 352100） 【摘要】目的 观察高通量透析对维持性血液透析( maintenance hemodialysis，MHD)患者血脂、钙磷代谢、炎症、营养等指标的影响。方法　将30例维持性透析患者随机分为高通量透析组和低通量透析组，比较2组治疗前及6个月后患者的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、钙（Ca）、磷（P）、超敏C-反应蛋白（hs-CRP）、血清白蛋白(ALB)水平。结果　与治疗前及低通量透析组比较，高通量透析组TG、TC、LDL、hs-CRP、P水平下降，Ca、ALB、HDL升高，其差异有统计学意义(均Plt;0.05)。结论　高通量透析可改善维持性血液透析患者血脂、钙磷代谢、炎症及营养状态。 【关键词】高通量透析 血液透析 脂代谢 炎症 营养情况 【中图分类号】R459.5 【文献标识码】A 【文章编号】2095-1752（2013）28-0153-02 Effect of high--flux hemodialysis on blood biochemical indices in maintenance hemodialysis patients XIE Mingbu, PAN Miao，Huang Zhi Ming Department of Nephrology，Ningde Municipal hospital，Ningde，Fujian 352100，China 【Abstract】Objective: To study the impact of high--flux hemodialysis on microinflammatory lipid profile and malnutrition in maintenance hemodialysis (MHD) patients. Methods: 30 patients on MHD were randomly divided into high--flux hemodialysis group and low--flux hemodialysis group. Total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, serum calcium,serum phosphorus, high sensitivity C-reactive protein ,serum albumin, were measured before treatment and after six months in two groups. Results: Total cholesterol, triglyceride, low density lipoprotein, serum phosphorus, high sensitivity C-reactive protein were reduced in high--flux hemodialysis group compared with low--flux hemodialysis group (P ＜0.05). serum calcium, high density lipoprotein, ,serum albumin, were increased in high--flux hemodialysis group compared with low--flux hemodialysis group ( P ＜ 0. 05). Conclusions: high--flux hemodialysis can improve Calcium and phosphorus metabolism lipid profile and microinflammatory malnutrition status function in hemodialysis patients. 【Key words】high--flux hemodialysis hemodialysis lipid profile microinflammatory malnutrition 心血管事件是维持性血液透析(maintenancehemodialysis，MHD)患者死亡主要原因，而MHD患