中国细菌耐药性现状（英文版）PPT.ppt

Bacterial Resistance in China ;Outline;;History of studies on antimicrobial resistance on Streptococcus pneumoniae ;Penicillin resistance in S. pneumoniae in China in late 1990’;Reasons causing the rapid increasing of penicillin resistance;Difference of penicillin resistance in S. pneumoniae isolated between adults and children;Resistance of S. pneumoniae to macrolides ;Antimicrobial resistance of S. pneumoniae isolated from children in Beijing, Shanghai, Guangzhou and Xi’an（2000－2001）;Mechanism of bacterial resistance:Mosaic PBP Genes in PRSP;Mechanisms of resistance to macrolides(Wang M. Diagn Microbial Infect Dis 2001; 39:187);;Trends of methicillin resistant Staphylococcus spp. (MRS) in China;Mechanism of MRSA;SummaryAntimicrobial resistance in gram-positive cocci;;Antimicrobial resistance rates of E. coli isolated in China in 2005 (n=3758);Antimicrobial resistance rates of K. pneumoniae in China in 2005 (n=2234);Extended-spectrum β-lactamases (ESBLs) in Enterobacteriaceae in China;Quinolone resistance rates in clinical isolates of E. coli in Shanghai;Mechanisms involved in quinolone resistance;Plasmid-mediated quinolone resistance: qnr determinats;Plasmid-mediated quinolone resistance;SummaryAntimicrobial resistance in gram-negative bacilli;;Importance of non-fermenters ;Percentage of non-fermenters in gram-negative bacilli in Shanghai hospitals(Wang F, et al. Int J Antimicrob Agents 2003; 22: 444);High incidence of non-fermenters in Gram-negative bacilli;Resistance profile of 6123 strains of non-fermenters against 8 antimicrobials in CHINET in 2005 (Wang F. Chin J Infect Chemother 2006; 6:289 );Trends in antimicrobial resistance rates among strains of P. aeruginosa isolated from Shanghai hospitals(%);Mechanisms of resistance to imipenem in P. aeruginosa;Trends in antimicrobial resistance rates among strains of Acinetobacter spp. isolated from Shanghai hospitals(%);Antimicrobial resistance rates among ICU strains of Acinetobacter spp. in