胺碘酮与普罗帕酮治疗阵发性室上性心动过速的用药效果对照研究.docVIP

精品论文 参考文献 胺碘酮与普罗帕酮治疗阵发性室上性心动过速的用药效果对照研究 湖南省溆浦县人民医院 湖南怀化 419300 【摘 要】目的：研究胺碘酮与普罗帕酮治疗阵发性室上性心动过速的用药效果对照。方法：取我院2014年1月-2015年12月阵发性室上性心动过速患者82例进行分组研究。胺碘酮组用胺碘酮治疗，普罗帕酮组用普罗帕酮治疗。比较两组患者阵发性室上性心动过速治疗总有效率、复律成功率；复律所需时间；患者不良事件发生率的差异。结果：普罗帕酮组跟胺碘酮组比较，阵发性室上性心动过速治疗总有效率、复律成功率相似，P＞0.05；普罗帕酮组相较于胺碘酮组复律所需时间更短，P＜0.05；普罗帕酮组相较于胺碘酮组不良事件发生率更高，P＜0.05。结论：胺碘酮与普罗帕酮治疗阵发性室上性心动过速均有一定效果，其中胺碘酮起效慢，但安全性较高，适合心功能不全和器质性心脏病者；普罗帕酮起效快但患者耐受较差，临床需根据患者情况选择用药。 【关键词】胺碘酮；普罗帕酮；阵发性室上性心动过速；用药效果；对照 【 abstract 】 objective：to study the amiodarone and propafenone in the treatment of paroxysmal room sex on the room tachycardia drug effect. Methods：in our hospital in January 2014 - December 2015 82 cases of patients with paroxysmal room sex on the room tachycardia（group research. Amiodarone group was treated with amiodarone，propafenone group treated with propafenone. Compare two groups of patients with paroxysmal room sex on the room tachycardia treatment success rate of total effective rate，answer law；Answer law required time. Incidence of adverse events in patients with difference. Results：propafenone and amiodarone group comparison，paroxysmal room sex on the room tachycardia treatment success rate of total effective rate，cardioerter similar，P gt; 0.05；Propafenone group compared with amiodarone cardioerter time needed for shorter，P lt; 0.05；Propafenone group compared with amiodarone group a higher incidence of adverse events，P lt; 0.05）. Conclusion：amiodarone and propafenone in the treatment of paroxysmal room sex on the room tachycardia all have certain effect，including amiodarone work slowly，but security is higher，suitable for cardiac insufficiency and organic heart disease. Patients with propafenone work fast but tolerance is poorer，clinical need to choose according to patients condition. 【 key words 】 amiodarone；Propafenone；Paroxysmal room sex on the room tachycardia；Drug effect；contrast 阵发性室上性心动过速为常见心律失常类型，多因其他心脏病所致，若不及时复律，可引发心律失常和心源性休克。目前临床治疗阵发性室上性心动过速方法多，如药物、机械治疗等[1