维持性透析患者继发性甲状旁腺功能亢进的影响因素.docVIP

精品论文 参考文献 维持性透析患者继发性甲状旁腺功能亢进的影响因素 江峡1 曾健2 　　(广东省佛山市南海区第二人民医院肾内科 广东佛山 528251) 　　【摘要】目的：探讨维持性透析患者继发性甲状旁腺功能亢进的影响因素。方法：选取我院2012年1月至2013年12月间收治的维持性透析患者100例，根据患者相关临床资料，同时依据患者甲状腺激素将其随机分为甲状旁腺功能亢进组和非甲状旁腺功能亢进组，分别为50例。所有患者均结合甲状旁腺激素、钙、磷和透析病程等相关因素进行分析。结果：低钙、高磷和高血肌酐水平及低血红蛋白等都是维持性透析患者继发性甲状旁腺功能亢进的影响因素。结论: 低钙、高磷和高血肌酐水平及低血红蛋白是影响维持性透析患者继发性甲状旁腺功能亢进的关键因素，因此，在治疗过程中应加强对于患者血液生化指标的监测。 　　【关键词】维持性透析患者 继发性甲状旁腺功能亢进 影响 　　【中图分类号】R581.1 【文献标识码】A 【文章编号】2095-1752（2014）17-0116-02 　　Effect of maintenance hemodialysis patients with secondary hyperparathyroidism factors 　　【Abstract】Objective: To explore the influence factors in maintenance hemodialysis patients with secondary hyperparathyroidism. Methods: selected admitted in our hospital in 2012 January to 2013 December 100 cases of maintenance hemodialysis patients, according to the relevant clinical data, on the basis of thyroid hormone in patients randomly divided into hyperparathyroidism group and non hyperparathyroidism group, respectively 50 cases. All patients were combined with the related factors of parathyroid hormone, calcium, phosphorus and dialysis duration analysis. Results: the low calcium, high phosphorus and high serum creatinine levels and lower hemoglobin are factors in maintenance hemodialysis patients with secondary hyperparathyroidism. Conclusion: the low calcium, high phosphorus and high serum creatinine levels and lower hemoglobin is the key factor, effect of maintenance hemodialysis patients with secondary hyperparathyroidism. Therefore, in the course of treatment should be to strengthen the monitoring for the biochemical indexes of blood. 　　【Key words】maintenance hemodialysis patients secondary hyperparathyroidism influence 　　近几年来，随着医疗事业的发展，血液透析技术得到了临床医学的广泛应用。而继发性甲状旁腺功能亢进在临床医学上，主要是指在慢性肾功能不全、Fanconi综合征、维生素D缺乏等条件下，甲状旁腺一直受到低血钙、高血磷和低血镁等物质的刺激，分泌出过多的甲状腺激素，从而有使血钙、血镁得到有效提高，同时也使血磷得到有效降低。因此，甲状旁腺功能亢进属于慢性肾功能衰竭患者常见的并发症，能够直接影响患者的生活品质，其特点具有甲状旁腺升高、低钙和高磷血症等特点。为了进一步探讨维持性透析患者继发性甲