Rosmarinic Acid, a New Polyphenol from Baccaurea ramiflora….pdfVIP

Antioxidants 2014, 3, 830-842; doi:10.3390/antiox3040830 OPEN ACCESS antioxidants ISSN 2076-3921 /journal/antioxidants Article Rosmarinic Acid, a New Polyphenol from Baccaurea ramiflora Lour. Leaf: A Probable Compound for Its Anti-Inflammatory Activity Talambedu Usha 1, Sushil Kumar Middha 1, Malay Bhattacharya 2, Prakash Lokesh 3 and Arvind Kumar Goyal 4,* 1 Department of Biotechnology, Maharani Lakshmi Ammanni College for Women, Bangalore-560012, India; E-Mails: ushatalambedu@ (T.U.); sushil.middha@ (S.K.M.) 2 Department of Botany, Kalimpong College, Kalimpong-734301, India; E-Mail: malaykpgc@ 3 Padmashree Institute of Management and Science, Bangalore-560060, India; E-Mail: connectloki@ 4 Bamboo Technology, Department of Biotechnology, Bodoland University, Kokrajhar-783370, India * Author to whom correspondence should be addressed; E-Mail: arvindgoyal210883@; Tel.: +91-825-600-2212. External Editors: Antonio Segura-Carretero and David Arráez-Román Received: 11 August 2014; in revised form: 20 November 2014 / Accepted: 20 November 2014 / Published: 3 December 2014 Abstract: Despite several pharmacological applications of Baccaurea ramiflora Lour., studies on the influence of its polyphenol content on pharmacological activity such as anti-inflammatory properties have been scarce. Here we evaluated in vitro antioxidant activity, poyphenolics by HPLC and the anti-inflammatory potential of the methanolic leaf extract of Baccaurea ramiflora (BME) and its protective effects in carrageenan-induced paw ed