梅花针联合得宝松外搽、窄谱中波紫外线治疗白癜风疗效观察.docVIP

精品论文 参考文献 梅花针联合得宝松外搽、窄谱中波紫外线治疗白癜风疗效观察 1.中山大学附属第五医院皮肤科 519000；2.中山大学附属第五医院呼吸科 519000 【摘 要】目的：观察梅花针联合得宝松外搽、窄谱中波紫外线（NB—UVB）、治疗白癜风的疗效。方法：将90例静止期白癜风患者随机分为治疗组和对照组各45例。治疗组采用梅花针局部叩刺后得宝松外搽联合照射窄谱中波紫外线；对照组采用得宝松皮损内局部注射联合窄谱中波紫外线照射。结果：治疗6个月，治疗组有效率为86.7％，对照组有效率为60％，治疗组疗效优于对照组，且治疗组无发生皮肤萎缩的不良反应。结论：梅花针联合得宝松外搽、NB—UVB照射治疗白癜风是一种疗效好，不良反应少、值得推广的治疗方案。 【关键词】白癜风；梅花针；得宝松；窄谱中波紫外线 [Abstract]Objective：To observe the effect of treating Vitiligo with plum blossom needle in combination with applying Compound Betamethasone topically and NB-UVB therapy.Methods：90 Vitiligo patients in diastasis period were divided randomly into the treatment group with 50 cases and the control group with 40 cases.The treatment group was treated with plum blossom needle first，and then was given a topical application of Compound Betamethasone and NB-UVB therapy.While the control group was treated with an injection of Compound Betamethasone and NB-UVB therapy.Result：After treatment of 6 months，the effective rate of treatment group was 86%，while the control group was 65%.The effectiveness of the treatment group was superior to that of the control group.Whatrsquo;s more，the side effect of dermatatrophia didnrsquo;t occur in the treatment group.Conclusion：Treating Vitiligo with plum blossom needle in combination with a topical application of Compound Betamethasone and NB-UVB therapy is an effective therapeutic schedule which has less side effects and is worth popularizing. [Key words]：Vitiligo；Plum blossom needle；Compound Betamethasone；NB-UVB 白癜风（vitiligo）是一种原发性性、局限性或泛发性皮肤色素脱失症[1]：，也是影响美容的常见皮肤病，易诊断，难治疗。我科采用梅花针局部叩刺后得宝松外搽联合窄谱中波紫外线（NB—UVB）治疗白癜风取得满意疗效，现将2010年6月～2012年6月，本院皮肤科门诊治疗白癜风的资料报告如下。 1资料与方法 1．1临床资料 1．1．1入选标准 ①临床上明确诊断为白癜风，且皮损在6个月内静止者；②年龄在2～70岁，性别不限；③2个月内未曾接受过系统治疗，2周内未曾接受过任何局部治疗者；④签署知情同意书，并能严格遵守治疗方案。 1．1．2排除标准 ①孕妇及哺乳期妇女；②有严重心、肝、肾及 其他严重系统性疾病者：③紫外线过敏者；④在试验期间，应用其他治疗白癜风的药物者；⑤因各种原因中途退出者，未按治疗方案系统治疗者；⑥皮损面积大于10cmtimes;10 cm者。（因梅花针叩刺时有一定的疼痛感，因此面积大者不适合梅花针的治疗） 1．I．3分组 共入选患者90例；所有患者均为寻常型白癜风，随