探讨阿托伐他汀联合辅酶Q10治疗对冠心病早期心功能减退患者心功能的临床效果.docVIP

精品论文 参考文献 探讨阿托伐他汀联合辅酶Q10治疗对冠心病早期心功能减退患者心功能的临床效果 大庆市人民医院 163316 摘要：目的 研究并讨论阿托伐他汀联合辅酶Q10治疗对冠心病早期心功能减退患者心功能的临床观察。方法 此次研究的对象是选择2011年3月至2014年4月我院收治的80例冠心病早期心功能减退患者，将其临床资料进行回顾性分析，并随机将其分成实验组和对照组，每组各40例，对照组患者采用阿托伐他汀进行临床治疗，实验组患者采用阿托伐他汀联合辅酶Q10进行临床治疗，治疗结束后，对比分析两组患者的心动图检测指标。结果 实验组患者与对照组患者治疗前后的E峰、A峰及E/A指标均明显优于治疗前（Plt;0.05），差异具有统计学意义；以健康人员的E峰、A峰及E/A指标作为参照，实验组患者治疗后的E峰、A峰及E/A指标改善情况优于对照组患者（Plt;0.05），差异具有统计学意义。结论 阿托伐他汀联合辅酶Q10治疗对冠心病早期心功能减退患者心功能的临床价值明显，能有效改善患者的心功能情况，促进患者恢复健康，改善患者的生存质量，故该治疗模式值得在临床实践过程中大力借鉴和推广。 关键词：阿托伐他汀；酶Q10；冠心病早期；心功能；影响 [Abstract] Objective To study and discuss the clinical effect of Atorvastatin Combined with coenzyme Q10 on cardiac function in patients with coronary heart disease in early stage of cardiac function. Method the study object is to choose a 2011 March to April 2014 admitted to our hospital 80 cases of coronary heart disease（CHD）early cardiac dysfunction in patients，the clinical data was retrospectively analyzed，and were randomly divided into experimental group and control group，each with 40 cases in each，the control group with atorvastatin for clinical treatment，patients in the experimental group using atorvastatin of atorvastatin and coenzyme Q10 for clinical treatment，after the end of treatment，comparative analysis of two groups of patients by echocardiography index. Results patients in the experimental group and control group before and after treatment in patients with the e peak，a peak and E / a indexes were significantly better than those before treatment（P lt; 0.05），the difference is statistically significant；the e peak health personnel，a peak and E / a index as a reference，after treatment，the patients in the experimental group E peak，a peak and E / a index improved better than control group（P lt; 0.05），the difference is statistically significant. Conclusion atorvastatin statins combined with coenzyme Q10 treatment of early cardiac dysfunction of coronary heart disease and the clinical value of cardiac function in patients with obvious，effectivel