Maternal allergic disease does not affect the phenotype of T and B cells or the immune response to allergens in neonates英文电子书.pdf

Allergy ORIGINAL ARTICLE E X P E R I M E N T A L A L L E R G Y A N D I M M U N O L O G Y Maternal allergic disease does not affect the phenotype of T and B cells or the immune response to allergens in neonates 1 1 1 2 3 1 E. Rindsjo , M. Joerink , C. Johansson , K. Bremme , V. Malmstrom A. Scheynius ¨ ¨ 1Department of Medicine Solna, Clinical Allergy Research Unit; 2Department of Women and Child Health, Division of Obstetrics and Gyne- cology; 3 Department of Medicine Solna, Rheumatology Unit, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden To cite this article: Rindsjo E, Joerink M, Johansson C, Bremme K, Malmstrom V, Scheynius A. Maternal allergic disease does not affect the phenotype of ¨ ¨ T and B cells or the immune response to allergens in neonates. Allergy 2010; 65: 822–830. Keywords Abstract allergic disease; cord blood; neonatal; uterine environment. Background: It is hypothesized that the in utero environment in allergic mothers can affect the neonatal immune responses. The aim of this study was to analyse Correspondence the effect of maternal allergic disease on cord blood mononuclear cell (CBMC) E. Rindsjo, Clinical Allergy Researc