Probiotics and immune health英文电子书.pdf

NIH Public Access Author Manuscript Curr Opin Gastroenterol. Author manuscript; available in PMC 2014 May 02. N Published in final edited form as: I H Curr Opin Gastroenterol. 2011 October ; 27(6): 496–501. doi:10.1097/MOG.0b013e32834baa4d. - P A A u Probiotics and immune health t h o r a b,c,d M Fang Yan and D.B. Polk a a n Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee u s b c Department of Pediatrics, University of Southern California, California, USA r i p c t Department of Biochemistry and Molecular Biology, University of Southern California, California, USA dSaban Research Institute, Children’s Hospital Los Angeles, Los Angeles, California, USA Abstract N Purpose of review—The beneficial effects of probiotics have been demonstrated in many I H - diseases. One of the major mechanisms of probiotic action is through the regulation of host P A immune response. This review highlights the recent scientific research findings that advance our A understanding of probiotic regulation of the host immune response with potential application for u t h disease prevention and treatment. o r M Recent findings—Probiotic genomic and proteomic studies have identified several genes and a specific compounds derived from probiotics, which mediate immunoregulatory effects. Studies n u s regarding the biological consequences of probiotics in host immunity suggested that they regulate c r the funct