PBS_PLA胸骨可降解材料组织相容性实验研究_华琨PBS_PLA胸骨可降解材料组织相容性实验研究_华琨.pdfVIP

32 20 V o.l 32, No. 20 2010 10 30 ACTA ACADEM IAE MEDICINAE M ILITARIS TERTIAE Oct. 30 2010 2205 文章编号:( 2010) PBS/PLA 1 2 2 1 1 2 华 琨 , 王小威 , 张 维 , 周 建 , 杨秀滨, 季君晖 ( 100037 , 1 2 ; 100190 , ) [] 目的 ( polylactic acid, PLA ) , [ poly( butyl succi ate), PBS] /( PLA)方法 60 SPF SD , 4: Sham PBS/PLAPBS PLA, 15 1, PBS PBS, PBS/PLA PBS/PLA , PLA PLA , Sham , 1481216 , , : ; H E ; M asso ; TUNEL 结果 1481216 PBS/PLA PBS PLA, 3 , ; PBS/PLA PBS PLA (P 005); 3 (P 005)结论 PBS/PLA PLA ; PBS/PLA [] ; ; ; [] R318. 08; R363. 27; R683. 1 [] A H istocompatibility of PBS/PLA blend as sternal fixation apparatus in rats 1 2 2 1 1 2 1 HuaKu , W a g X iaow ei, Zha gW ei, Zhou Jia , Y a g X iubi , Ji Ju hu i ( Departm e t of Cardiac Surgery, C ard iovas cular I stitute Fuw aiH osp ital, Ch i ese Academy of M ed ical Scie ces Peki g U io M edical College, Beiji g, 100037; 2 I stitute of Physics a d Chem istry, Ch i ese Academ y of Scie ces, Beiji g, 100190, Chi a) [Abstract ] O bjective To i vestigate the in vivo ster al fixatio of poly( butyl succi ate) ( PBS) a d polylactic acid ( PLA) alloym aterial by compari g its b iocompatib ility of polylactic acid ( PLA ). M e thods Sixty SD ratsw ere ra dom ized i to 4 groups ( n = 15). PBS, PLA a d PBS /PLA alloyw ere mi pla ted subcuta eously i the correspo di g rat dorsum respectively. Sham groupw as desig ed as the