绿茶儿茶素和血压：一项系统综述和荟萃分析的随机对照试验.pdf

Eur J Nutr (2014) 53:1299–1311 DOI 10.1007/s00394-014-0720-1 REVIEW Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials Saman Khalesi • Jing Sun • Nicholas Buys • Arash Jamshidi • Elham Nikbakht-Nasrabadi • Hossein Khosravi-Boroujeni Received: 12 December 2013 / Accepted: 13 May 2014 / Published online: 27 May 2014 Springer-Verlag Berlin Heidelberg 2014 Abstract included. A random-effect model was chosen to calculate Purpose Although previous literature has reported that the effect of combined trials. regular green tea consumption may improve blood pres- Result Thirteen studies were included in the meta-ana- sure, the evidence from these studies is not consistent. The lysis. Green tea consumption significantly changed systolic present study systematically reviewed randomised con- blood pressure, by -2.08 mm Hg (95 % CI -3.06, -1.05), trolled trials and examined the effect of green tea con- and diastolic blood pressure, by -1.71 mm Hg (95 % CI sumption on blood pressure using meta-analysis. -2.86, -0.56), compared to the control. Changes in lipid Methods Search of ProQuest, PubMed, Scopus and profile, blood glucose and body mass index were also Cochrane Library (CENTERAL) was conducted, to iden- assessed in the meta-analysis. A significant reduction was tify eligible articles. Articles from 1995 to 2013 were found in total cholesterol (-0.15 mmol/L [95 % CI -0.27, -0.02]) and low-density lipoprotein cholesterol Electronic supplementary material The online version of this (-0.16 mmol/L [95 % CI -0.22, -0.09]