有哪些信誉好的足球投注网站deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure赤字在水迷宫性能和氧化应激引起的海马和纹状体极低频磁场暴露.pdfVIP
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deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure赤字在水迷宫性能和氧化应激引起的海马和纹状体极低频磁场暴露
Deficits in Water Maze Performance and Oxidative Stress in the Hippocampus and Striatum Induced by Extremely Low Frequency Magnetic Field Exposure 1. 1. 2. 1 1 1 1 Yonghua Cui , Zhiqiang Ge , Joshua Dominic Rizak , Chao Zhai , Zhu Zhou , Songjie Gong , Yi Che * 1 Medical College of Soochow University, Suzhou, People’s Republic of China, 2 Laboratory of Primate Neuroscience Research, Key Laboratory of Animal Models, Kunming Institute of Zoology, Chinese Academy of Science, Kunming, People’s Republic of China Abstract The exposures to extremely low frequency magnetic field (ELF-MF) in our environment have dramatically increased. Epidemiological studies suggest that there is a possible association between ELF-MF exposure and increased risks of cardiovascular disease, cancers and neurodegenerative disorders. Animal studies show that ELF-MF exposure may interfere with the activity of brain cells, generate behavioral and cognitive disturbances, and produce deficits in attention, perception and spatial learning. Although, many research efforts have been focused on the interaction between ELF-MF exposure and the central nervous system, the mechanism of interaction is still unknown. In this study, we examined the effects of ELF-MF exposure on learning in mice using two water maze tasks and on some parameters indicative of oxidative stress in the hippocampus and striatum. We found that ELF-MF exposure (1 mT, 50 Hz) induced serious oxidative stress in the hippocampus and striatum and impaired hippocampal-dependent spatial learning and striatum-dependent habit learning. This study provides evidence for the associati
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