crystallization study and comparative in vitro–in vivo hydrolysis of pla reinforcement ligament结晶研究和比较在vitro-in体内水解的解放军强化韧带.pdfVIP

Int. J. Mol. Sci. 2011, 12, 6597-6618; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Crystallization Study and Comparative in Vitro–in Vivo Hydrolysis of PLA Reinforcement Ligament Theodore Beslikas 1, Ioannis Gigis 1, Vasilios Goulios 1, John Christoforides 1, George Z. Papageorgiou 2 and Dimitrios N. Bikiaris 2,* 1 2nd Orthopaedic Department, Aristotle University of Thessaloniki, Thessaloniki, Macedonia 54124, Greece; E-Mails: beslikastheo@in.gr (T.B.); jgigis@otenet.gr (I.G.); bill.goulios@gmail.gr (V.G.); hristofo@med.auth.gr (J.C.) 2 Laboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Macedonia 54124, Greece; E-Mail: gzpap@chem.auth.gr * Author to whom correspondence should be addressed; E-Mail: dbic@chem.auth.gr; Tel.: +30-2310-997812; Fax: +30-2310-997667. Received: 27 June 2011; in revised form: 24 September 2011 / Accepted: 28 September 2011 / Published: 10 October 2011 Abstract: In the present work, the crystallization behavior and in vitro–in vivo hydrolysis rates of PLA absorbable reinforcement ligaments used in orthopaedics for the repair and reinforcement of articulation instabilities were studied. Tensile strength tests showed that this reinforcement ligament has similar mechanical properties to Fascia Latta, which is an allograft sourced from the ilio-tibial band of the