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controlled positioning of cells in biomaterials—approaches towards 3d tissue printing控制细胞的定位biomaterials-approaches对3 d组织印刷
J. Funct. Biomater. 2011, 2, 119-154; doi:10.3390/jfb2030119 OPEN ACCESS Journal of Functional Biomaterials ISSN 2079-4983 /journal/jfb/ Review Controlled Positioning of Cells in Biomaterials—A roaches Towards 3D Tissue Printing Silke Wüst, Ralph Müller and Sandra Hofmann * Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland; E-Mails: siwuest@ethz.ch (S.W.); ram@ethz.ch (R.M.) * Author to whom correspondence should be addressed; E-Mail: sahofmann@ethz.ch; Tel.: +41-44-633-7082; Fax: +41-44-632-1214. Received: 26 May 2011; in revised form: 29 June 2011 / Accepted: 12 July 2011 / Published: 4 August 2011 Abstract: Current tissue engineering techniques have various drawbacks: they often incorporate uncontrolled and imprecise scaffold geometries, whereas the current conventional cell seeding techniques result mostly in random cell placement rather than uniform cell distribution. For the successful reconstruction of deficient tissue, new material engineering approaches have to be considered to overcome current limitations. An emerging method to pr
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