comparison of standard 1.5 t vs. 3 t optimized protocols in patients treated with glatiramer acetate. a serial mri pilot study比较标准的1.5吨和3 t优化协议与醋酸glatiramer患者。.pdfVIP
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comparison of standard 1.5 t vs. 3 t optimized protocols in patients treated with glatiramer acetate. a serial mri pilot study比较标准的1.5吨和3 t优化协议与醋酸glatiramer患者。
Int. J. Mol. Sci. 2012, 13, 5659-5673; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Comparison of Standard 1.5 T vs. 3 T Optimized Protocols in Patients Treated with Glatiramer Acetate. A Serial MRI Pilot Study Robert Zivadinov 1,2,*, David Hojnacki 2, Sara Hussein 1, Niels Bergsland 1, Ellen Carl 1, 1 1 1 2 Jacqueline Durfee , Michael G. Dwyer , Cheryl Kennedy and Bianca Weinstock-Guttman 1 Buffalo Neuroimaging Analysis Center, State University of New York, Buffalo, NY 14203, USA; E-Mails: sarahussein@ (S.H.); npbergsland@ (N.B.); ecarl@ (E.C.); jdurfee@ (J.D.); mgdwyer@ (M.G.D.); ckennedy@ (C.K.) 2 The Jacobs Neurological Institute, Department of Neurology, University at Buffalo, State University of New York, Buffalo, NY 14203, USA; E-Mails: hojnacki@ (D.H.); BWeinstock-Guttman@ (B.W.-G.) * Author to whom correspondence should be addressed; E-Mail: rzivadinov@; Tel.: + 1-716-859-7040; Fax: + 1-716-859-4005. Received: 22 March 2012; in revised form: 23 April 2012 / Accepted: 3 May 2012 / Published: 10 May 2012 Abstract: This study explored the effect of glatiramer acetate (GA, 20 mg) on lesion activity using the 1.5 T standard MRI protocol (single dose gadolinium [Gd] and 5-min delay) or optimized 3 T protocol (triple dose of
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